Protein Alignment GluRIIC and KaiR1D

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Alignment Length: 876
• Identity: 297/876 - (33%)
• Similarity: 459/876 - (52%)
• Gaps: 71/876 - (8%)

  Fly     6 LLLGCMWSAFFMCRSRGQQINIGAFFY--DDELELEKEFMTVVNAING-----PESEQTMRFYPL 63
            |:|.|.     ..:|....|.||..|:  ||..||  .|...|:.||.     |.|:...:
  Fly    16 LILNCR-----KAQSLPDIIKIGGLFHPADDHQEL--AFRQAVDRINADRSILPRSKLVAQ---- 69

  Fly    64 IKRLKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQAEK 128
            |:|:.|.| |....:..|.|::.||||||||.|...:..|..:|::..|||:| :..|..::.|
  Fly    70 IERISPFD-SFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLE-NRWDYRLRRE- 131

  Fly   129 PNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREVHNDVVRVRK 193
               ...:||||....|||||.|||:::||:.|||:|:.:|  ...|||:||:...:....:.||:
  Fly   132 ---SCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENND--GIVRLQELLKAHGMTPFPITVRQ 191

  Fly   194 FHKDDDFRVMWKSIR--GERRVVLDCEPNMLVELLNSSTEFGLTGQYNHIFLTNLETYTDHLEEL 256
            .....|:|.:.|.|:  .|..:||||....:.|:|..:.:.|:...|:...:|:|:.:|.:|:|.
  Fly   192 LSDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEF 256

  Fly   257 AADNETFAVNITAARL----LVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLIHDLIHDALQLF 317
            ...    ..|||..||    :|:.....:|:....:.:..|:....|:..      |::||:.||
  Fly   257 RYG----GTNITGFRLINEKIVSDVVRQWSIDEKGLLRSANLTTVRSETA------LMYDAVHLF 311

  Fly   318 AQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLARLMKGTSGVNNTNFRTSILQFDEDGQ 382
            |::..:..  ...::.:..|:||    |..||..|..|...||    :......|::::||..|.
  Fly   312 AKALHDLD--TSQQIDIHPISCD----GQSTWQHGFSLINYMK----IVEMKGLTNVIKFDHQGF 366

  Fly   383 RITFNIEVYD--PLDGIGIAIWD---PRG-----QITQLNVDVKAQ-KKMIYRVATRIGPPYFSY 436
            |..|.:::.:  |.....|..|:   |.|     ..:|...:::|. |.....|.|.:..||...
  Fly   367 RTDFMLDIVELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMR 431

  Fly   437 NETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINND 501
            .|:|  :.|:||..::|||||||..|::.:||.|....|.|..||.|:|.|.:|||:|.|::...
  Fly   432 KESA--IPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQR 494

  Fly   502 AHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVM 566
            |.:.|.|||||..|:.|||||.|||.||||||..|.......|.::|:|...:|||::..:...:
  Fly   495 ADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGV 559

  Fly   567 TFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEAT 631
            :.|..|:|:.:..:|  |...:...|.:|:|:.:.|..|..:.|:|..|||.||::...||....
  Fly   560 SVLLFILAKFTPYEW--PAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGI 622

  Fly   632 WWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETVYRL 696
            ||.|.:|:.:|||||||||||..:|:..|.:.:||:.|.::|:|.:.||||.....||..:.|:.
  Fly   623 WWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQR 687

  Fly   697 AFNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHYAIA 761
            .::.|.:..||.:|..|.|||:||.|.:|.|.||||:|::||..|:||:|..||.....|.|.||
  Fly   688 MWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIA 752

  Fly   762 VPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNP--NASCFEE--PDPDATPDMTFEELRGIFY 822
            .|..:.||:.::..||||.|.|:|:.||.||||..  ...|..|  ....|..::....:.|:|.
  Fly   753 TPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFV 817

  Fly   823 TLYAGILIAFLIGITEFLVYVQQVALEERLT 853
            .|..|:.:|.:|.:.||:...::||:||||:
  Fly   818 VLMGGMGVACVIAVCEFVWKSRKVAVEERLS 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	117/405 (29%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	153/370 (41%)
		Lig_chan	554..827	CDD:459656	103/276 (37%)
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	117/402 (29%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	153/373 (41%)