Protein Alignment GluRIIC and Ir76b

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 129/615 - (20%)
• Similarity: 218/615 - (35%)
• Gaps: 141/615 - (22%)

  Fly   364 GVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIGIAIWDPRGQITQLNVDVKAQKKMI------ 422
            |.|.|....:.|..|.|.....|:.:.             |...:..:|......::|:
  Fly    32 GENGTLSPVTELPMDVDASEAGFDADA-------------PVETLETINRKKPKLREMLDWIGGK 83

  Fly   423 -YRVATRIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKE 486
             .|:||....| .||.|...    .|..:..|.:..:||.:.:...|.|..|...|...|    .
  Fly    84 HLRIATLEDFP-LSYTEVLE----NGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDNIIG----S 139

  Fly   487 TKQWNGIIGEIINND-AHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAP 550
            ...::..:.|::|:. ..:....:.....:::.|.::...:..|..|:..:.|....:....|||
  Fly   140 PSDFDRSLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASGSGLLAP 204

  Fly   551 FGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQ---------WRIHNTGWL 606
            |  |.|:||||.|.::.....|.|.|                :|.|:         :.:.:..|.
  Fly   205 F--EFWVWILILVSLLAVGPIIYALI----------------ILRNRLTGDGQQTPYSLGHCAWF 251

  Fly   607 TVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKK 671
            ...::|..|..:.|.:...|:..||||||..|:.:.|||||.||||.||.......:.|:..:.|
  Fly   252 VYGALMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNK 316

  Fly   672 VKFGTIYGGSTYNLLADSNETVYRLAFNLMNN-----DDPSAYTKDNLEGVDRVRKNRGDYMFLM 731
             .|.::.||.....:..:||::..|...:.||     |:    |.|.....:.|.||  .|:|:.
  Fly   317 -HFVSMRGGGVEYAIRTTNESLSMLNRMIQNNYAVFSDE----TNDTYNLQNYVEKN--GYVFVR 374

  Fly   732 E--------------TTTLEYHREQ-NCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSE 781
            :              ..|:.:..|: :|......|.|.:|....|.|.|:.........:|.|.|
  Fly   375 DRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKKRTFAYPIGSNLSQLFDPELLHLVE 439

  Fly   782 RGELYDLKQKWWKNPNASCFEEPDPDATP-DM--TFEELRG-----IFYTLYAGILIAFLIGITE 838
            .|.:..|.::          ..|..:..| |:  |..:||.     .:|.:.||...|..:..||
  Fly   440 SGIVKHLSKR----------NLPSAEICPQDLGGTERQLRNGDLMMTYYIMLAGFATALAVFSTE 494

  Fly   839 FLVYVQQVALEERLTFKDAFKKEIRFVLCVWNNRKPIVAGTPISSVRTTPRRSLDKSLDRTPKSS 903
            .:                     .|:|    |:|:             ...:.....:.||| :.
  Fly   495 LM---------------------FRYV----NSRQ-------------EANKWARHGIGRTP-NG 520

  Fly   904 RRVVIGRSSEEMREMAQGSGSSSGSNNAGR 933
            :.|...|.....|.:..|.|...|::..|:
  Fly   521 QSVAPSRWLRGWRRLNSGHGQLLGASTHGQ 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	8/44 (18%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	93/400 (23%)
		Lig_chan	554..827	CDD:459656	74/309 (24%)
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	21/117 (18%)
		Lig_chan	209..458	CDD:459656	66/281 (23%)