Protein Alignment GluRIIC and Ir7c

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Alignment Length: 676
• Identity: 130/676 - (19%)
• Similarity: 220/676 - (32%)
• Gaps: 196/676 - (28%)

  Fly   282 SLPYGYVTQRDN------------IVYESSDPPRTLIHDLIHDALQLFAQSWRNASFFYPDRMVV 334
            ||.|..|...||            :.:.:|...|.|.:|||..||...:.:.|.......||:.:
  Fly    10 SLVYALVWAIDNYYGMATSTPLAVVQFPTSRESRRLHNDLIDAALGRSSGTGRIQFLLEDDRVEM 74

  Fly   335 PRITCDFAASGGRTWAMGRYLARLMKGTSGVNNTNFRTSIL--QFDEDGQRITFNIEVY-----D 392
            .....|.....|.|   ||.:|.....:.   .:.||..:.  |.....:|..|.:.:|     .
  Fly    75 TETDTDPPPPSGLT---GRPIAIWFLDSL---RSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQ 133

  Fly   393 PLDGIGIAIWDPRGQITQ--LNVDVKAQKKMIYRVAT--RIGPP---------YFSYNETARELN 444
            |::.:.|..   |..:..  |||:|..|:.....:.|  ..||.         |.::.:.|...|
  Fly   134 PMESLKIMF---RRLLNMYVLNVNVFLQRDGTVHLYTYYPYGPHHCQSSLPVYYTAFQDLAAPAN 195

  Fly   445 ------------LT---------------------------GNALYQGYAVDLIDAIARHVGFEY 470
                        ||                           |.....|....:..::|..:.|..
  Fly   196 GFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGLIFRSLAERMNFTI 260

  Fly   471 VFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAY 535
            ..|...|:..|::..: ..:.||:..:::.:.::.......::||...:..:..:....: :|..
  Fly   261 KLVEQKDKNRGEILPD-GNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPI-VLVV 323

  Fly   536 KSPHVEKTLDAYLAPFGGEVWIWILISV---FVMTFLKTIVARISKMDWENPHPCNRDPEVLENQ 597
            .|......:.....||...:|..||:|:   ||:..|..|.|.          |..|: .||..:
  Fly   324 PSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITAL----------PGLRN-LVLGRR 377

  Fly   598 WRIHNTG-WLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIA 661
            .|:...| |   ||::.......|:....|.....|.:..:|:..:||..|...|...:|...|.
  Fly   378 NRLPFMGMW---ASLLGGLALYNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIK 439

  Fly   662 NLKDLSAQKKVKF------GTIYGGS----TYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEG 716
            :|.::.| |..:|      .||:..|    .::.:....|::||    |.:.|||
  Fly   440 SLSEVLA-KDYEFRILPALRTIFKDSMPTTNFHAVLSLEESLYR----LRDEDDP---------- 489

  Fly   717 VDRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHYAI------AVPFG---------- 765
                    |..:.|::.|..::      |.||...|   :|..:      ..|..
  Fly   490 --------GITVALLQPTVNQF------DFRSGPNK---RHLTVLPDPLMTAPLTFYMRPHSYFK 537

  Fly   766 ----------------AEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPDMTF 814
                            |.||......|.::|:|..|                 ||.|     ::.
  Fly   538 RRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNL-----------------EPKP-----LSI 580

  Fly   815 EELRGIFYTLYAGILIAFLIGITEFL 840
            ..|.|||.......|:|.::.|.|.|
  Fly   581 WRLSGIFVCCAGLYLVALIVFILEIL 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	32/145 (22%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	81/466 (17%)
		Lig_chan	554..827	CDD:459656	65/318 (20%)
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	9/62 (15%)
		Lig_chan	343..592	CDD:459656	65/316 (21%)