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Protein Alignment GluRIIC and Gria2

DIOPT Version :9

Sequence 1:	NP_608557.4	Gene:	GluRIIC / 33275	FlyBaseID:	FBgn0046113	Length:	940	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	892	Identity:	256/892 - (28%)
Similarity:	413/892 - (46%)	Gaps:	122/892 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ILLLGCMWSAFFMCRSRGQQINIGAFF---YDDELELEKEFMTVVNAINGPESEQTMRFYPLIKR 66
            :||...:|...|...|  ..|.||..|   .|.|....:     |..:....||  .|..|.|..
  Rat     9 VLLSPVLWGLIFGVSS--NSIQIGGLFPRGADQEYSAFR-----VGMVQFSTSE--FRLTPHIDN 64

  Fly    67 LKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQAEKPNH 131
            |:..: |..:....|.....||.||||...|.:.:.:...|.:..:..|......:|      .|
  Rat    65 LEVAN-SFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG------TH 122

  Fly   132 QMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLL-------------QLRE 183
            ...:.:.|.   |..|...:::.:.|.||..:||:|  |..:.||.:|             .:..
  Rat   123 PFVIQMRPD---LKGALLSLIEYYQWDKFAYLYDSD--RGLSTLQAVLDSAAEKKWQVTAINVGN 182

  Fly   184 VHNDVVRVRKFHKDDDFRVMWK--SIRGERRVVLDCEPNMLVELLNSSTEFGLTGQYNHIFLTNL 246
            ::||       .||:.:|.:::  .::.||||:||||.:.:.::::.....|...:..|..:.||
  Rat   183 INND-------KKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 240

  Fly   247 ETYTDHLEELAADNETFAVNITAARL----LVNPDPPPYSLPYGYVTQRDNIVYESSDP---PRT 304
             .:|        |.:...:....|.:    :|:.|.   ||...:: :|.:.:.|...|   ..|
  Rat   241 -GFT--------DGDLLKIQFGGANVSGFQIVDYDD---SLVSKFI-ERWSTLEEKEYPGAHTAT 292

  Fly   305 LIHD--LIHDALQLFAQSWRNASFFYPDRMVVPR--ITCDFAASGGRTWAMGRYLARLMK----- 360
            :.:.  |.:||:|:..:::||   ....|:.:.|  ...|..|:....|..|..:.|.:|
  Rat   293 IKYTSALTYDAVQVMTEAFRN---LRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354

  Fly   361 GTSGVNNTNFRTSILQFDEDGQRITFNIEV-------------YDPLDGIGIAIWD-PRGQITQL 411
            |.||         .::||::|:||.:.|.:             :..:|.:.:.:.: |.|.
  Rat   355 GLSG---------NIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGN---- 406

  Fly   412 NVDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVA 476
              |....:.....|.|.:..||....:. .|: |.||..|:||.|||...||:|.||:|....|.
  Rat   407 --DTSGLENKTVVVTTILESPYVMMKKN-HEM-LEGNERYEGYCVDLAAEIAKHCGFKYKLTIVG 467

  Fly   477 DQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVE 541
            |.:||..|.:||.|||::||::...|.:.|..||||..|:..:||:.|||.||:||:..|....:
  Rat   468 DGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 532

  Fly   542 KTLDAYLAPFGGEVWIWIL---ISVFVMTFLKTIVARISKMDWENPH-PCNRDPEVLE--NQWRI 600
            ..:.::|.|...|:|:.|:   |.|.|:.||   |:|.|..:|.... ...|:.:..|  |::.|
  Rat   533 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFL---VSRFSPYEWHTEEFEDGRETQSSESTNEFGI 594

  Fly   601 HNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKD 665
            .|:.|.::.:.|..||||.|||...|:....||.|.:||.:|||||||||||..:|...|.:.:|
  Rat   595 FNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAED 659

  Fly   666 LSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMFL 730
            ||.|.::.:||:..|||......|...|:...:..|.:.:||.:.:...|||.||||::|.|.:|
  Rat   660 LSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYL 724

  Fly   731 METTTLEY-HREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWK 794
            :|:|..|| .:.:.||...||.....|.|.||.|.|:...:.:::|:|||:|:|.|..||.|||.
  Rat   725 LESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWY 789

  Fly   795 NPNASCFE--EPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEF 839
            : ...|..  ....:.|..::...:.|:||.|..|:.:|.|:.:.||
  Rat   790 D-KGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEF 835

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.