DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GluRIIC and Ir41a

DIOPT Version :9

Sequence 1:	NP_608557.4	Gene:	GluRIIC / 33275	FlyBaseID:	FBgn0046113	Length:	940	Species:	Drosophila melanogaster
Sequence 2:	NP_995744.4	Gene:	Ir41a / 2768714	FlyBaseID:	FBgn0040849	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	69/382 - (18%)
Similarity:	129/382 - (33%)	Gaps:	117/382 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   431 PPY----FSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYG---KLDKE-T 487
            |||    .:.:..|:::.::|.:.::...:|         |.|...|....:|:.   ::|.. .
  Fly   221 PPYTVIKHNMSTNAQDMGVSGESDFKNVYID---------GTETRIVLNFCEQFNCTIQIDSSAA 276

  Fly   488 KQW---------NGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKT 543
            ..|         :|.:|.:||..|.:.|..:.......|.:|.::..::.|::.|.   |...:.
  Fly   277 NDWGKVYPNMSGDGALGMLINRKADICIGAMYSWYEDYTYLDLSMYLVRSGITCLV---PAPLRL 338

  Fly   544 LDAY--LAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWL 606
            ...|  |.||...:|..||:.:                       |            ...|| |
  Fly   339 TSWYLPLEPFKETLWAAILLCL-----------------------C------------AEATG-L 367

  Fly   607 TVASIMTAGCDILPRSPQVRMFEATWW---------IFAIIIANSYTANLAAFLTSSKMEGSIAN 662
            .:|........:||.      :...||         .|.:.|:.|  .|..|:..:.::......
  Fly   368 VLAYKSEQALYVLPG------YREGWWTCTSFGVCTTFKLFISQS--GNSKAYSLTVRVLLFACF 424

  Fly   663 LKDLSAQKKVKFGTIYGGSTYNLLA-----DSNETVYRLAFNLM----NND--------DPSAYT 710
            |.||.      ..:||||...::|.     ::.:||.||.|:.:    |::        ...|..
  Fly   425 LNDLI------ITSIYGGGLASILTIPSMDEAADTVTRLRFHRLQWAANSEAWVSAIRASDEALV 483

  Fly   711 KDNLEGVDRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHYAIAVPFGAE 767
            ||.|.          ::....:...|...::|:..:....|:....|:||....|.:
  Fly   484 KDILY----------NFHIYSDDELLRLAQDQHMRIGFTVERLPFGHFAIGNYLGPQ 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141
		PBP2_iGluR_Kainate	423..794	CDD:270432	69/382 (18%)
		Lig_chan	554..828	CDD:278489	42/240 (18%)
Ir41a	NP_995744.4	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462657
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840