Protein Alignment GluRIIC and Ir76b

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: XP_061511889.1
• Gene: Ir76b / 1280702
• VectorBaseID: AGAMI1_009346
• Length: 658
• Species: Anopheles gambiae
• Alignment Length: 613
• Identity: 134/613 - (21%)
• Similarity: 227/613 - (37%)
• Gaps: 128/613 - (20%)

  Fly   394 LDGIGIA--IWDPRGQIT----QLNVDVKAQKK-------------MIYRVATRIGPPYFSYNET 439
            :|..|||  .||  |..|    ||.:|..|:.|             ...||.|....| .||.
Mosquito    68 VDAQGIAPVEWD--GNETTEYYQLEMDASAEVKEREMQELRRRLTGTTLRVTTLQDWP-LSYT-- 127

  Fly   440 ARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEII----NN 500
               :.:.|..:..|.|.:|::.:.....|.|..|.......|..       |.:.|.::    |.
Mosquito   128 ---VKINGTYIGAGVAFELLEFLMEKFNFTYELVMPEQNIVGSS-------NDMAGSVLQLLTNG 182

  Fly   501 DAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFV 565
            .|.|.:..|.|....:..:.::.. :..|..|:....|....:....||||..:|||.||:|:..
Mosquito   183 TADMAVSFLPILADARQHIRYSTG-LDEGEWIMIMVRPMESASGSGLLAPFNRDVWILILVSLLA 246

  Fly   566 M--TFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMF 628
            :  .....::.|         |...:|.|.:  .:.:.:..|....::|..|..:.|.....|:.
Mosquito   247 VGPIIYGLLILR---------HRLTKDKEQI--IYTLPHCVWFVYGALMKQGSTLSPTGDSTRIL 300

  Fly   629 EATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETV 693
            .|:||||..|:.:.|||||.||||.||....|.|.:|:..::| :|.||.||:....:.:.:|.:
Mosquito   301 FASWWIFITILTSFYTANLTAFLTLSKFTLPINNAEDVRRKEK-QFVTIRGGAIEYAIKNRDEAL 364

  Fly   694 YRLA---------FNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMFLMETTTLEY----------- 738
            ..|:         |....||      .|.|  .|:|.|.  :|:|:.:...:::
Mosquito   365 NALSVLVDKRLVDFTTNVND------SDTL--ADKVAKQ--NYVFVRDRPAIDHMIYADYLVRRK 419

  Fly   739 ----HREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERG----ELYDLKQKWWKN 795
                :...:|...:....|.:::.|...|...|:.......:||:.|.|    :|:|      :.
Mosquito   420 INPKNERVHCPYATATTPFLKRNRAFGYPPNTEWNRIFDPELLKMVEGGIVKYKLHD------RL 478

  Fly   796 PNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEF-LVYVQQVALEERLTFKDAFK 859
            |.|....:........:...:|...::.:..|.:.:.::..:|. ..|:.|..|.|:|..:...:
Mosquito   479 PKAEICPQNLGGTERQLKNRDLVMTYFVMVTGFVTSIVVFASELGFRYLNQRKLNEQLAQQQQQQ 543

  Fly   860 KEIRFVLCVWNNRKPIVAGTPISSVRTTPRRS-LDKSL---DRTPKSSRRV-----------VIG 909
            ::.:               .|.|....|.|.| |.|..   |..|.....|           |:|
Mosquito   544 QQDQ---------------QPTSKKLATERISYLGKQFTTGDSPPPPYAEVFSRHQQQQQLGVLG 593

  Fly   910 RSSEEMREMAQGSGSSSGSNNAGRGEKE 937
            .|....:....|||...|:..||...::
Mosquito   594 DSERTGKLFDDGSGGLYGAGGAGGANRQ 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	7/16 (44%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	92/404 (23%)
		Lig_chan	554..827	CDD:459656	67/302 (22%)
Ir76b	XP_061511889.1	None