Protein Alignment GluRIIC and grik3

DIOPT Version :9

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: XP_031752773.1
• Gene: grik3 / 100498426
• XenbaseID: XB-GENE-6050069
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 929
• Identity: 276/929 - (29%)
• Similarity: 460/929 - (49%)
• Gaps: 129/929 - (13%)

  Fly     1 MWQRILLLGCMWSAFFM----CRSRGQQINIGAFFYDDELELEKEFMTVVNAINGPESEQTMRF- 60
            :|:.:|....:|..:..    |:.....|.||..|.    .||.....:|:|     .||..||
 Frog     8 LWRMVLQYWAVWFCYIFWLQSCQGMPHVIRIGGIFE----HLEGPTGQLVSA-----EEQAFRFS 63

  Fly    61 -----------------YPLIKRLKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCN 108
                             |. |:|:...| |......|||.:..||.||||||..::|:.|..:||
 Frog    64 ASIINRNRTLLPNTTLTYD-IQRINLYD-SFEANRKACDQLALGVVAIFGPSHSSSSNAVQSICN 126

  Fly   109 STGIPHIEFDISDEGIQAEKPNHQMT------LNLYPAQAILSKAYADIVQNFGWRKFTIVYDAD 167
            :..:||         ||....:|.:.      :||||..|.||.|..|:||...||..|:||  |
 Frog   127 ALEVPH---------IQVRWKHHPLDNRDSFYVNLYPDYASLSHAILDLVQFLKWRSATVVY--D 180

  Fly   168 DARAAARLQDLLQLREVHNDVVRVRKF-HKDDDFRVMWKSI-RG-ERRVVLDCEPNMLVELLNSS 229
            |:....|||:|:.....:|..:::|:. .:.:|.|.:.|.: || |.|::.||...|..::|..:
 Frog   181 DSTGLIRLQELIMAPARYNIRLKIRQLPPESEDARPLLKEMKRGREFRIIFDCSHTMAAQILRQA 245

  Fly   230 TEFGLTGQYNHIFLTNLETYTDHLEELAADNETF---AVNITAARLLVNPDPPPYSLPYGYVTQR 291
            ...|:..:|.|...|.|:.|       |.|.|.:   .||:|..|:| |.|.|       ||:
 Frog   246 MAMGMMTEYYHYIFTTLDLY-------ALDLEPYRYSGVNLTGFRIL-NVDNP-------YVS-- 293

  Fly   292 DNIV-------YESSDPPRTLIHD--------LIHDALQLFAQSWRNASFFYPDRMVVPRITCDF 341
             :||       ::::..|.:.:.|        |.:||:.:.:..::.|     .:|.|..:.|
 Frog   294 -SIVDKWSMERHQATPKPESGLLDGIMTTDAALTYDAVHIVSVCYQRA-----PQMTVNSLQC-- 350

  Fly   342 AASGGRTWAMGRYLARLMK--------------GTSGVNNTNFRTSILQFDEDGQRITFNIEVYD 392
              ...:.|..|......:|              .|||: .|:|...|:...|||..   .:..::
 Frog   351 --HRHKAWRFGSRFMNFIKEAQWEGLTGRIVFNKTSGL-RTDFDLDIISLKEDGLE---KVGTWN 409

  Fly   393 PLDGIGIAIWDPRGQITQLNVDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYAVD 457
            |.||:.|. ...||:...::..: ..:.:|  |.|.:..||..:..:  :..|.|...::|:.:|
 Frog   410 PSDGLNIT-ETARGRGPNISESL-TNRTLI--VTTVLEEPYVMFKRS--DTPLFGKDRFEGFCID 468

  Fly   458 LIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFT 522
            |:..||..:||:|....|.|.:||..| |..||||::.|:|::.|.:.:..||||..|:..:||:
 Frog   469 LLKKIAEILGFDYDIRLVEDAKYGSQD-EKGQWNGLVKELIDHKADLAVAPLTITHVREKVIDFS 532

  Fly   523 VPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPC 587
            .|||.||:|||..|:.....::.::|.|...::|::||::...::.:..::||.|..:|.:.|||
 Frog   533 KPFMTLGISILYRKANGTAPSVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYDAHPC 597

  Fly   588 NRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLT 652
            |...:|:||.:.:.|:.|..|.::|..|.:::|::...|:....||.|.:||.:|||||||||||
 Frog   598 NPGTDVVENNFTLLNSFWFAVGALMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLT 662

  Fly   653 SSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEGV 717
            ..:||.:|.:..||:.|.|:::|.:..|:|.|....|:.:.:...:..|:: .|||..|.|.||:
 Frog   663 VERMESAIDSADDLAKQTKIEYGAVVDGATMNFFKKSHISTFEKMWAFMSS-RPSALVKSNEEGI 726

  Fly   718 DRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSER 782
            .||..  .||..|||:|.:||..::||:|..:|.....|.|.|..|.|:.||..:|:|||:|.|.
 Frog   727 QRVLS--ADYALLMESTAIEYITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDRISIAILQLQEA 789

  Fly   783 GELYDLKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVA 847
            .|::.:|::||:  :..|.||.:.:|:. :..:.:.|||..|..|::::.::.:.||:..:::.|
 Frog   790 DEIHKMKERWWR--SGGCPEEKNKEASA-LGIQNMGGIFIVLAGGLILSVVVAMAEFVYKLRKTA 851

  Fly   848 LEERLTFKDAFKKEIRFVL 866
            ..|:.:|......|||..|
 Frog   852 EREQRSFCSTMADEIRLSL 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377	117/436 (27%)
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141	17/112 (15%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	132/370 (36%)
		Lig_chan	554..828	CDD:278489	96/273 (35%)
grik3	XP_031752773.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	1	1.010	-	-		D60688at33208
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930