DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and CPR6

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_013317.1	Gene:	CPR6 / 850914	SGDID:	S000004206	Length:	371	Species:	Saccharomyces cerevisiae

Alignment Length:	188	Identity:	74/188 - (39%)
Similarity:	104/188 - (55%)	Gaps:	21/188 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGING---------TSYVGSRFHRVVDR 83
            :.:.|:....||.|||.|.|:..:.|||..||..:| .|..|         .||.||.||||:..
Yeast     5 KTFFDISIGGKPQGRIVFELYNDIVPKTAENFLKLC-EGNAGMAKTKPDVPLSYKGSIFHRVIKD 68

  Fly    84 FLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWL 148
            |:.|.||..|.:|||..|||.:.|.||:  ..|:|::|..|.|||.||:|||.|.::|.|....|
Yeast    69 FMCQFGDFTNFNGTGGESIYDEKFEDEN--FTVKHDKPFLLSMANAGPNTNGSQAFITCVPTPHL 131

  Fly   149 DGKHTVFGKVLEGMDTIYAIEDVKTDTD-DFPVEPVVISNCGEIPTEQFEFYPDDFNI 205
            ||||.|||:|::|...:..||:.:.|.: :.|:..|.|.:||.:        |||:.:
Yeast   132 DGKHVVFGEVIQGKRIVRLIENQQCDQENNKPLRDVKIDDCGVL--------PDDYQV 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	69/170 (41%)
CPR6	NP_013317.1	cyclophilin_ABH_like	4..173	CDD:238907	69/170 (41%)
		TPR repeat	219..264	CDD:276809
		TPR repeat	269..303	CDD:276809
		TPR repeat	308..334	CDD:276809
		TPR_1	311..341	CDD:395414
		TPR repeat	342..368	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810