DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and Ppie

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_062362.1	Gene:	Ppie / 56031	MGIID:	1917118	Length:	301	Species:	Mus musculus

Alignment Length:	163	Identity:	75/163 - (46%)
Similarity:	100/163 - (61%)	Gaps:	4/163 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIV 92
            ::|||:|...||.|||...|...:.|.|..|||.:|... .|..:.||.|||::.:|:.||||..
Mouse   141 QVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHE-KGFGFKGSSFHRIIPQFMCQGGDFT 204

  Fly    93 NGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGK 157
            |.:|||..||||..|.||:  ..::|..||.|.|||.||:|||.||::|.....||||||.|||:
Mouse   205 NHNGTGGKSIYGKKFDDEN--FILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGE 267

  Fly   158 VLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGE 190
            |.||:|.:..|| .:...|..|.:.|:|::|||
Mouse   268 VTEGLDVLRQIE-AQGSKDGKPKQKVMIADCGE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	72/160 (45%)
Ppie	NP_062362.1	RRM	<5..194	CDD:223796	22/53 (42%)
		RRM_PPIE	8..80	CDD:240793
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..141		75/163 (46%)
		cyclophilin_ABH_like	140..298	CDD:238907	72/160 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810