DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and ppil4

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_001121802.1	Gene:	ppil4 / 554886	ZFINID:	ZDB-GENE-030131-6251	Length:	454	Species:	Danio rerio

Alignment Length:	184	Identity:	64/184 - (34%)
Similarity:	87/184 - (47%)	Gaps:	25/184 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISI-- 102
            :|.|...|:.:..||...||..:|  .|...:|  ...|.|...|::|.|| ..|.|.|..|:
Zfish     9 LGDIVIDLYTEERPKASLNFLKLC--KIKYYNY--CLIHNVQRDFIIQTGD-PTGTGRGGESVFC 68

  Fly   103 --YGDY--FPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTT-VGAKWLDGKHTVFGKVLEGM 162
              |||.  |.:.:|...::|.:.|.:.|.|.|.|.:|.||.:|| ....:|||.|||||:|.|||
Zfish    69 KLYGDQARFFESEKMPRIKHRKKGTVSMVNNGSDQHGSQFLITTGENVDYLDGVHTVFGEVTEGM 133

  Fly   163 DTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPV 216
            |.:..|.:...|.|..|.:.:.| |...|..:.|    ||        .|||||
Zfish   134 DVLAKINETFVDNDFIPFQDIRI-NHTVILDDPF----DD--------PAGLPV 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	55/155 (35%)
ppil4	NP_001121802.1	cyclophilin_RRM	4..169	CDD:238902	59/177 (33%)
		RRM	172..>320	CDD:223796	3/3 (100%)
		RRM_PPIL4	237..319	CDD:240681
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810