DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and ppil2

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_957285.2	Gene:	ppil2 / 393966	ZFINID:	ZDB-GENE-040426-1096	Length:	524	Species:	Danio rerio

Alignment Length:	164	Identity:	62/164 - (37%)
Similarity:	91/164 - (55%)	Gaps:	11/164 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGG 89
            |..:.|:.:..||   |.:...|.....||...||..:|.:|.    |.|:.|||.:..|::|||
Zfish   276 VKKKGYVRLHTNK---GDLNVELHCDKVPKAGENFIKLCKKGY----YDGTVFHRSIRNFMIQGG 333

  Fly    90 DIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTV 154
            | ..|.|||..|.:|..|.||.:. .:.|...|.|.|||.||:||..||::|.....:||.||:|
Zfish   334 D-PTGTGTGGESFWGKPFKDEFRP-NLSHTGRGILSMANSGPNTNKSQFFITFRSCAYLDRKHSV 396

  Fly   155 FGKVLEGMDTIYAIEDVKTD--TDDFPVEPVVIS 186
            ||:|:.|::|:.|:|:|::|  ||....|..::|
Zfish   397 FGRVVGGLETLSAMENVESDPKTDKPKSEIKILS 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	61/162 (38%)
ppil2	NP_957285.2	Ubox	42..96	CDD:128780
ppil2	NP_957285.2	cyclophilin_RING	281..440	CDD:238904	61/159 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810