DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ninaA and CG7747

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	195	Identity:	73/195 - (37%)
Similarity:	100/195 - (51%)	Gaps:	33/195 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AVASGLSFTVTSRI----------------YMDVKHNKK-------PVGRITFGLFGKLAPKTVA 57
            |||:  |||.|:.:                |..||  ||       .:|.:...||....|:...
  Fly   245 AVAA--SFTSTAMVPVSQIEAAIIDDDLVKYERVK--KKGYVRLNTNLGPLNLELFCDQTPRACD 305

  Fly    58 NFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPG 122
            ||...|..|.    |....|||.:..|:||||| ..|.|:|..||:|..|.||.|. .:.|...|
  Fly   306 NFIKHCANGY----YNNVMFHRSIRNFIVQGGD-PTGSGSGGESIWGKKFEDEFKP-NLTHTGRG 364

  Fly   123 YLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISN 187
            .|.|||.||:|||.||::|....|.||||||:|||::.|:||:..:|:::.|..|.|:|.::|.:
  Fly   365 VLSMANSGPNTNGSQFFITYRSCKHLDGKHTIFGKLVGGLDTLQKMENIEVDNKDRPIEDIIIES 429

Fly 188 187
Fly 430 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	66/184 (36%)
CG7747	NP_611113.1	RING	25..238	CDD:302633
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	61/155 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810