Protein Alignment ninaA and PPWD1

DIOPT Version :10

• Sequence 1: NP_476656.1
• Gene: ninaA / 33271
• FlyBaseID: FBgn0002936
• Length: 237
• Species: Drosophila melanogaster
• Sequence 2: NP_056157.1
• Gene: PPWD1 / 23398
• HGNCID: 28954
• Length: 646
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 77/221 - (34%)
• Similarity: 101/221 - (45%)
• Gaps: 58/221 - (26%)

  Fly     9 ILCSAFLAVASGLSFTVTSRIYMDVKH---------------NKKP------------------- 39
            |:|::|          ..:|.||..|.               |:||
Human   438 IVCTSF----------KKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSD 492

  Fly    40 -------VGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGT 97
                   :|.|...||....||||.||   |:...|| .|.|..|||::..|::|.|| ..|.|.
Human   493 SAIIHTSMGDIHTKLFPVECPKTVENF---CVHSRNG-YYNGHTFHRIIKGFMIQTGD-PTGTGM 552

  Fly    98 GSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGM 162
            |..||:|..|.||..: .:.|:||..|.|||.|.:|||.||::|.|...|||.||||||:|.:||
Human   553 GGESIWGGEFEDEFHS-TLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGM 616

  Fly   163 DTIYAIEDVKTD-TDDFPVEPVVISN 187
            :.:..|.:||.: ..|.|.|.|.|.|
Human   617 EVVQRISNVKVNPKTDKPYEDVSIIN 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:469651	74/203 (36%)
PPWD1	NP_056157.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		WD 1	80..118
		WD40	<89..319	CDD:441893
		WD 2	124..162
		WD40 repeat	136..177	CDD:293791
		WD 3	168..208
		WD40 repeat	191..219	CDD:293791
		WD 4	213..252
		WD40 repeat	226..277	CDD:293791
		WD 5	271..309
		WD40 repeat	283..326	CDD:293791
		WD 6	345..386
		WD 7	401..453		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	455..490		3/34 (9%)
		cyclophilin_WD40	495..643	CDD:238908	67/154 (44%)