DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and cyn-1

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_506561.1	Gene:	cyn-1 / 179936	WormBaseID:	WBGene00000877	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	80/200 - (40%)
Similarity:	114/200 - (56%)	Gaps:	14/200 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICL- 64
            ||.||....|....|..||     ...:::.||...::|.||:|..||..:.|||..|||.:|.
Worm     1 MKFLLRASSLAGQSLRFAS-----QRPKVFFDVSIGEEPAGRVTMELFNDVVPKTAENFRALCTG 60

  Fly    65 -RGIN----GTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYL 124
             :|:.    ...:.||:|||::..|::||||....:|||..||||:.|.||:  ..::|..||.|
Worm    61 EKGVGEQGVALHFKGSKFHRIIPEFMIQGGDFTRHNGTGGESIYGNKFKDEN--FDLKHTGPGCL 123

  Fly   125 GMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCG 189
            .|||.||:|||.||::.||...||||.|.|||:|.:||..:..||.:.: ....|.:.|.|::||
Worm   124 SMANAGPNTNGSQFFICTVDTPWLDGGHVVFGQVTDGMSVVKKIEKMGS-RSGAPAKTVTIADCG 187

  Fly   190 EIPTE 194
            |:.:|
Worm   188 ELKSE 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	68/167 (41%)
cyn-1	NP_506561.1	cyclophilin_ABH_like	22..187	CDD:238907	68/167 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820