DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and cyn-4

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_496337.1	Gene:	cyn-4 / 174674	WormBaseID:	WBGene00000880	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	70/201 - (34%)
Similarity:	100/201 - (49%)	Gaps:	27/201 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VASGLSFTVTSRI--------------YMDVKHNK-----KPVGRITFGLFGKLAPKTVANFRHI 62
            ||:|.:.||.:.:              |..||.|.     ...|.:...||....||...||...
Worm   246 VAAGFTSTVMAPVTSNKAAVLDNDTVRYSRVKKNAFVRLVTNFGPLNLELFAPKVPKACENFITH 310

  Fly    63 CLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMA 127
            |..|.    |..::|||::..|::|||| ..|.|.|..||:...|.||..: ...|:..|.|.||
Worm   311 CSNGY----YNNTKFHRLIKNFMLQGGD-PTGTGHGGESIWDKPFSDEFIS-GFSHDARGVLSMA 369

  Fly   128 NRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDT-DDFPVEPVVISNCGEI 191
            |:|.:|||.||::|....|:||.|||:||:::.|.||:..||.::|:. .|.|:..|||.. .|:
Worm   370 NKGSNTNGSQFFITFRPCKYLDRKHTIFGRLVGGQDTLTTIEKLETEEGTDVPMVSVVIMR-AEV 433

  Fly   192 PTEQFE 197
            ..:.||
Worm   434 FVDPFE 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	62/181 (34%)
cyn-4	NP_496337.1	Ubox	45..96	CDD:128780
cyn-4	NP_496337.1	cyclophilin_RING	281..440	CDD:238904	61/166 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810