DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ninaA and cyn-5

DIOPT Version :9

Sequence 1:	NP_476656.1	Gene:	ninaA / 33271	FlyBaseID:	FBgn0002936	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	NP_001379232.1	Gene:	cyn-5 / 173374	WormBaseID:	WBGene00000881	Length:	204	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	93/202 - (46%)
Similarity:	121/202 - (59%)	Gaps:	17/202 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKSLLNRIILCSAFLAV--------ASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVA 57
            |||||    :.:|.|||        |.|..  ||.::|.|::...||:|||..|||||..|||..
Worm     1 MKSLL----VVAAVLAVGALAQGDDAKGPK--VTDKVYFDMEIGGKPIGRIVIGLFGKTVPKTAT 59

  Fly    58 NFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPG 122
            ||..:..:. .|..|.||:||||:..|::||||...|||||..||||:.|.||:  ..::|...|
Worm    60 NFIELAKKP-KGEGYPGSKFHRVIADFMIQGGDFTRGDGTGGRSIYGEKFADEN--FKLKHYGAG 121

  Fly   123 YLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISN 187
            :|.|||.|.||||.||::|||...||||:|.||||:|||||.:..||..:....|.|.:.|:|:.
Worm   122 WLSMANAGADTNGSQFFITTVKTPWLDGRHVVFGKILEGMDVVRKIEQTEKLPGDRPKQDVIIAA 186

  Fly   188 CGEIPTE 194
            .|.|..:
Worm   187 SGHIAVD 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ninaA	NP_476656.1	cyclophilin	27..189	CDD:294131	78/161 (48%)
cyn-5	NP_001379232.1	cyclophilin	29..188	CDD:412213	78/161 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920