Protein Alignment aru and eps8l3a

DIOPT Version :10

• Sequence 1: NP_722663.1
• Gene: aru / 33268
• FlyBaseID: FBgn0029095
• Length: 805
• Species: Drosophila melanogaster
• Sequence 2: XP_002666161.1
• Gene: eps8l3a / 100334248
• ZFINID: ZDB-GENE-091204-460
• Length: 646
• Species: Danio rerio
• Alignment Length: 784
• Identity: 178/784 - (22%)
• Similarity: 285/784 - (36%)
• Gaps: 264/784 - (33%)

  Fly    46 LRGGGAHGGGGGGGDYSGDDRSG--GGEE---------RERLESDLHDKPTYL------------ 87
            ||.....|..||   |:...||.  ..:|         |...:|..|.:..|.
Zfish     2 LRDSSPFGWSGG---YAESLRSSVTAADESSSDVLDLSRPSAKSIYHQRKEYAESVNRQMHQFQH 63

  Fly    88 -LEHLATFTVNKESGIVYPADGMRRLLQLEKTTGIWSQKMQLCLDYQWVLIMDYETGNIIERFPA 151
             :|||.|..::.:. :....|.:.||..|:.|..:|.|.:.|.:....:.:.|.||..::|.:|.
Zfish    64 RVEHLFTCELDGQQ-LCDVDDCLERLKYLDATGRVWGQDVILEVQDAALRLADIETREVLESWPL 127

  Fly   152 SLVQEPTAFTSNDAMELYNNILVFIVSGGGGSRSEMHIFQSQSVSAVHLVEDLKQLRSGKMITQQ 216
            |.|.|..|....   .:|:::|...|...|.....:.:|||:::.|.:|.:||::|      .|.
Zfish   128 SCVLELKAVLDE---SVYDSLLTVSVQERGSRTVSVFMFQSETLRADYLKKDLQRL------LQN 183

  Fly   217 RGATPTQSGGGGASSMAMMMSKTSSSSSHSRVELHQHREQRAERERERDRD----------RERE 271
            ....|.||.    ||.|.:.:.|..:|..:........::.|||....|.|          |...
Zfish   184 SRDDPRQSN----SSKAAVGNITQKNSRRASPPPELILQRPAERWAAPDYDDSPVATPPTSRNNS 244

  Fly   272 SHHHM-----------HQRSS---MEQYGIRAGVGVSGDDVAHISGETDSEHGGIGGGGATERDE 322
            :|..:           |::::   .|:..:|                              |...
Zfish   245 THTKVVAPPPQTKTPPHKQTTPPRTEEPPVR------------------------------EAPP 279

  Fly   323 TSSTSSEKYERDVAVLNHCFDDIEKFIARLQHAAAASRELERRRRNRKSKKRDPGEGLLTLRTRP 387
            .....:|: ||:|.:|||..:|||.|:.||   .|.:.:::::::.:|.:|...|         .
Zfish   280 PQKPYTER-ERNVDILNHLINDIEAFVGRL---TAVAPKMDKKKKKQKKQKAVKG---------M 331

  Fly   388 PHEKEFVDIFAKFKLSFNLLAKLKAHIHDPNAPELVHFLFTPLALIVEASSDTYY-ESQLPARVV 451
            |.::||.....|.|::||||.||:..|.:|:|.||.|.||:.|.|:|      |: ...||..:|
Zfish   332 PSDEEFTVCLRKIKMAFNLLGKLQGKIDNPSAAELTHCLFSILELVV------YHCNEDLPPSIV 390

  Fly   452 NPLLTREAINLLINCVTSKETELWRSLGDAWVIPRDQW---KDDVGSYHPVFLDGWSPDYLINDE 513
            .||...|.:..|....|.:|..||:||||||.||..:|   .||:.::.|||.|||.|..:.|.|
Zfish   391 APLFEPECVVFLSEEATPEEDHLWQSLGDAWNIPSTKWPEDDDDIPTFTPVFDDGWEPPAIRNPE 455

  Fly   514 LEPPPNSPPAH--VSKRRLEVQAGSGLNGRGGGGYDDYDSGNGMNMAMGIEKYTIHHGNDGLRER 576
                    |.:  :||:....::.|
Zfish   456 --------PTYKQISKQEPAYKSIS---------------------------------------- 472

  Fly   577 ERERDRERAGAISASDFNARSELSFDSIEGRGGGAAGHGHGHGHGPGAGPTLSAITAGLQNLHTR 641
              :.|..|..........|..||..:..|
Zfish   473 --KEDTPRTSVARQMSRTAEPELEPEQSE------------------------------------ 499

  Fly   642 ESRSGNGYGAGAGPGPSSELGGGGRGLPNVSDDQMLESWLEDLQATGAKIVLVTYPRTANNDKEL 706
                                      ||                   |..:...:..:|.||:||
Zfish   500 --------------------------LP-------------------ASFMRAIFDFSARNDREL 519

  Fly   707 SVMRGEYLEILDDTRKWWKARNMRGQVAHVPHTIVTPFNFGDGDGAQFYGQQQQPPTGPTGP--G 769
            |:.:||.|::||.::||||.:|.|||:..||:.::           |...|:::....|:.|  .
Zfish   520 SITKGEELQLLDMSKKWWKVKNQRGQIGFVPNNML-----------QQQNQEEEKEEAPSAPALN 573

  Fly   770 NKSR 773
            .|||
Zfish   574 RKSR 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aru	NP_722663.1	PTB_EPS8	82..215	CDD:269921	34/145 (23%)
		SH3_Eps8	691..744	CDD:212698	21/52 (40%)
eps8l3a	XP_002666161.1	PTB_EPS8	59..185	CDD:269921	34/135 (25%)
		PTZ00436	<178..282	CDD:185616	21/143 (15%)
		SH3_Eps8	504..554	CDD:212698	21/49 (43%)
		SAM_EPS8-like	571..636	CDD:188939	3/7 (43%)