DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13950 and LGALS8

DIOPT Version :9

Sequence 1:	NP_001334728.1	Gene:	CG13950 / 33267	FlyBaseID:	FBgn0031289	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_006490.3	Gene:	LGALS8 / 3964	HGNCID:	6569	Length:	359	Species:	Homo sapiens

Alignment Length:	379	Identity:	73/379 - (19%)
Similarity:	130/379 - (34%)	Gaps:	124/379 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VPF----------GHVLIVSGRVKPHPNKISLDLTDNVNAQNESETVFLKIEANFREGQIIRSMF 66
            :||          |.::::.|.|....::..:||.:..:.:..::..| .....|:....|....
Human    17 IPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAF-HFNPRFKRAGCIVCNT 80

  Fly    67 QPGGGWQQEEISKNWKCDGPKNPLQPGQSFTFRVAVLQRCFEIYVNDQ---LYGSFEFVKF-PKQ 127
            .....|.:|||:.:       .|.:..:||...:.||:..|::.||.:   |||.    :. |::
Human    81 LINEKWGREEITYD-------TPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGH----RIGPEK 134

  Fly   128 INYVRTYG-------------DFE-------KITQFHHRML---------------FPLVFPRTL 157
            |:.:..||             |.:       ::|:.....:               ...:.|||:
Human   135 IDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTV 199

  Fly   158 MCPDKVAFQSDVPRRYETGTVVAMECIAKGPPTTEFSICFQCN---DTGRTV------------- 206
            ....|   .|.|........:..|..::|..|     ...:.|   ..||||
Human   200 YTKSK---DSTVNHTLTCTKIPPMNYVSKRLP-----FAARLNTPMGPGRTVVVKGEVNANAKSF 256

  Fly   207 -----------LRFHVNFDRTTVSRSYQREDNSFALSDEETEGE-------FPFVRGKLFKIAFG 253
                       :..|:| .|..: :::.|  |||.   :|:.||       |||..|..|::...
Human   257 NVDLLAGKSKDIALHLN-PRLNI-KAFVR--NSFL---QESWGEEERNITSFPFSPGMYFEMIIY 314

  Fly   254 LGDRAFLIAVNGQYFTYYNFPGRPFSISTLKCFTNEVGDFAVRSLEYHSDSPLL 307
            ...|.|.:||||.:...|....:..|              ::.:||.:.|..||
Human   315 CDVREFKVAVNGVHSLEYKHRFKELS--------------SIDTLEINGDIHLL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13950	NP_001334728.1	None
LGALS8	NP_006490.3	Gal-bind_lectin	18..151	CDD:278752	29/144 (20%)
LGALS8	NP_006490.3	Gal-bind_lectin	236..356	CDD:214904	32/140 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010