Protein Alignment CG4291 and WBP4

DIOPT Version :10

• Sequence 1: NP_608551.1
• Gene: CG4291 / 33264
• FlyBaseID: FBgn0031287
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: XP_005266302.1
• Gene: WBP4 / 11193
• HGNCID: 12739
• Length: 407
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 116/392 - (29%)
• Similarity: 192/392 - (48%)
• Gaps: 71/392 - (18%)

  Fly     1 MTEYWKSNERKFCDFCKCWLSDNKASVAFHESGKRHKMNVAKRITDISRNSEKSERERQKMDAEI 65
            :.:||||..:||||:||||::||:.||.|||.||.||.||||||::|.:.|....:|.:|...|.
Human    32 LADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEF 96

  Fly    66 RKMEEAAMKSYAQDVHSRG---DMTARSINTVMRA-TATAAASGGAHSFAGRSRQVDPMR---LE 123
            ..||.||:|:|.:|:...|   ::...||..|... ..|:.::........:.|:.||.:   :|
Human    97 AAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVE 161

  Fly   124 GLSDE---------------------EEDQRRVAPGKVTSDAAVPEASLWVEGKSDEGHTYYWNV 167
            |::.|                     :.|.::.|           ..::||||.|::|.|||:|.
Human   162 GITSEGYHYYYDLISGASQWEKPEGFQGDLKKTA-----------VKTVWVEGLSEDGFTYYYNT 215

  Fly   168 KTNESVWKPPKE--GYLSYEEYERINQLA---IDQQQISQA-------EESLKFRANVDEEVARV 220
            :|.||.|:.|.:  .:.|.....::|:.:   :|:.:.|.:       :|:.:...:.:.|..::
Human   216 ETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKI 280

  Fly   221 N-REKMKAFRRTDNPKEKKQKEERRQTFKTEEEAATKEI------GQWQTV--EVKAPEQPIDWQ 276
            . :||.|......:|:.:|:|..::|......|..:|.:      |:||.:  ||::.|: :|.:
Human   281 KFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEE-VDLE 344

  Fly   277 LPKT--DYYSAAPVVSASSEPEPPVKKFKEKTIGGLDEEIAATAPATFKRKFIRKG---NSRQRA 336
            ||.|  :|.|.:   .|....||.| .|||||:..|.......|| .||::....|   |.|||.
Human   345 LPSTENEYVSTS---EADGGGEPKV-VFKEKTVTSLGVMADGVAP-VFKKRRTENGKSRNLRQRG 404

  Fly   337 ED 338
            :|
Human   405 DD 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4291	NP_608551.1	zf-U1	10..44	CDD:389966	23/33 (70%)
		WW	152..177	CDD:459800	14/24 (58%)
WBP4	XP_005266302.1	zf-U1	39..75	CDD:368798	23/35 (66%)
		PRP40	159..>227	CDD:227435	20/78 (26%)