DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment drongo and ZIGA4

DIOPT Version :9

Sequence 1:	NP_001162848.1	Gene:	drongo / 33263	FlyBaseID:	FBgn0020304	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_001184942.1	Gene:	ZIGA4 / 837390	AraportID:	AT1G08680	Length:	651	Species:	Arabidopsis thaliana

Alignment Length:	771	Identity:	173/771 - (22%)
Similarity:	263/771 - (34%)	Gaps:	232/771 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKQDDKYLLALRELVASGTGSNRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGLTPPHRVKSIS 70
            :::::|.:..|.:|     ..||:|.:|...||.||..|..:|||..|||:.|..|  |||||:|
plant     8 EERNEKIIRGLMKL-----PPNRRCINCNSLGPQYVCTTFWTFVCMACSGIHREFT--HRVKSVS 65

  Fly    71 MATFTQDEIDFLRSHGNELCAKTWLGLWDPKRAVHQQEQ----------RELMMDKYERKRYYLE 125
            |:.||..|::.|::.||:...:.:|..||     ||:::          ||.:.:.|.:|:|
plant    66 MSKFTSKEVEVLQNGGNQRAREIYLKNWD-----HQRQRLPENSNAERVREFIKNVYVQKKY--- 122

  Fly   126 PASPLKSLANAVNLKSSAPATNHTQN----GHQNGYASIHLTPP-----------------AAQR 169
                  :.||..: |.|..:.:|..:    ...|.|.|...:||                 ..:.
plant   123 ------AGANDAD-KPSKDSQDHVSSEDMTRRANSYHSYSQSPPYDYQYEERRYGKIPLGFTGKS 180

  Fly   170 TSANGLQKVANSSSNSSGKTSSSISRPHYNHQNNSQNNNHDAFGLGGGLSSLNSAGSTSTGALSD 234
            .|..||...|:|...|.|:.|        :|....|.:|.|         |...|...|..:..|
plant   181 ASVKGLHAKASSFVYSPGRFS--------DHMFEDQFSNED---------SAPRASDYSVSSAGD 228

  Fly   235 --TSSCASNGFGADCDFVA-DF------GSANIFDATS-ARSTGSPAVSSVSSVGSSNGYAKVQP 289
              .|...|..|..:.:|.: .|      .|.|:|.... .|:|.|.:|.||.|     .:..::.
plant   229 PFRSDIQSPNFQQEAEFRSPQFQHSNAPPSENLFPGRQHQRTTSSGSVRSVDS-----NFMSIKS 288

  Fly   290 IRAAHLQQQQQLQQQLHQQQLLNGNGHQG-TENFADFDHAPIYNAVAPPTFNDWISDWSRRGFHD 353
            ..:..|.:.....:|       |....|| |.|     |.|:   ||..|             ..
plant   289 YTSGGLGEAVSESRQ-------NTGSQQGKTSN-----HVPL---VAEST-------------KA 325

  Fly   354 PFD-----------DCDDSPPGARPPAPAPAPAQVPAVSSPLP------TVREEP-----ELA-- 394
            |.|           ..|...|...|.:|.....|.|...|..|      .:.::|     ||:
plant   326 PIDLFQLPGAPVAQSVDTFQPSIAPRSPPVNLQQAPQTYSFTPANSFAGNLGQQPTSRPSELSAP 390

  Fly   395 ----WNFWEDEMRIEAQEKESQTKQPELGYSFSISTTTPLSPSNPFLPYLVSEEQHRNHPEKPSF 455
                |..:::.|. .|:.....|...:......|......|.|....||..:.:||.
plant   391 KNEGWASFDNPMP-AAKSTNVITSPGDFQLELKIEEILQPSTSMQLPPYPSTVDQHA-------- 446

  Fly   456 SYSLFSSISNSSQEDQADDHEMNVLNANFHDFFTWSA--------PLQNGHTTSPPKGGNAAMAP 512
                 .||.:..|||.:     |||.....:...|:|        ||.:.........|.:..:.
plant   447 -----LSIPSPWQEDLS-----NVLKDVVDNPQPWNAFPDSIEANPLDSSRNIHQQVDGASTSSY 501

  Fly   513 SEDRYAALKDLDEQLRELKASESATETPTPTSGNVQATDAFGGALNNNPNPFKGQQQQQLSSHV- 576
            :.|.    :.|:.|:.|   |:..:...|.|:.....:.|||...|....|...::..|   ||
plant   502 NTDH----QHLESQVLE---SQELSNDGTQTTRIPAGSSAFGFPGNIGMAPSYSEEAWQ---HVN 556

  Fly   577 ----VNPFQQQQQQQHQQN--------LYGQLTLIPNAYGSSSQQQMGHHLLQQQQQQQQSFFNF 629
                .|||......:...|        |.|.|..|                     |..|:|.|.
plant   557 EQKSANPFDLPYDSEFDSNDMFLDMSSLQGALPDI---------------------QTPQAFLNG 600

  Fly   630 NNNGFAISQGLPNGCGFGSMQPAPVMANNPFA-ASGAMNTN------------NPF 672
            .:..:..:..:|      |..|||.:|....| .:|..:||            |||
plant   601 VSQPWLAADSVP------SYLPAPAVAQGGLAYMAGQASTNSAAQGPVAFTGGNPF 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drongo	NP_001162848.1	ArfGap	15..126	CDD:279720	42/120 (35%)
ZIGA4	NP_001184942.1	PLN03119	2..651	CDD:178666	173/771 (22%)
ZIGA4	NP_001184942.1	ArfGap	12..126	CDD:279720	43/134 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I3023
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002634
OrthoInspector	1	1.000	-	-		otm2488
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.860