Protein Alignment drongo and Agap2

DIOPT Version :10

• Sequence 1: NP_001162848.1
• Gene: drongo / 33263
• FlyBaseID: FBgn0020304
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_075415.2
• Gene: Agap2 / 65218
• RGDID: 628844
• Length: 1186
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 64/268 - (23%)
• Similarity: 112/268 - (41%)
• Gaps: 34/268 - (12%)

  Fly     4 VRKKQDDKYLLALRELVASGTGSNRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGL-TPPHRVK 67
            |:.:.|.:......:.:.:..| |..|.|||...||:.::.:|:.:|..|||:.|.| |...||:
  Rat   915 VKLRTDSQSEAVAIQAIRNAKG-NSTCVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVR 978

  Fly    68 SISMATFTQDEIDFLRSHGNELCAKTW----LGLWDPKRAVHQQEQRELMMDKYERKRYYLEP-- 126
            |:.:..:.::....|.:.||:...:.|    .|...|.|...::|:...:..||| :..:|.|
  Rat   979 SLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAKPTRDSSREERESWIRAKYE-QLLFLAPLG 1042

  Fly   127 --ASPL-KSLANAVNLKSSAPA---TNHTQNGHQNG-------YASIHLTPPAAQRTSANGLQKV 178
              ..|| :.|..||..:..|..   ..|.::|..:.       .:.:||   ||:.......|.:
  Rat  1043 TTEEPLGRQLWAAVEAQDVAAVLLLLAHARHGPLDTSVEDPQLRSPLHL---AAELAHVVITQLL 1104

  Fly   179 ANSSSNSSGKTSSSISRPHYNHQNNSQ-----NNNHDAFGLGGGLSSLNSAGS----TSTGALSD 234
            ....::.:.:.:...:...|..|..||     ...|...|.||..::..||.:    |:|.:...
  Rat  1105 LWYGADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGEGGSTATTPSAATTPSITATPSPRR 1169

  Fly   235 TSSCASNG 242
            .||.||.|
  Rat  1170 RSSAASLG 1177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drongo	NP_001162848.1	ArfGap_AGFG	15..123	CDD:350067	30/112 (27%)
Agap2	NP_075415.2	Interaction with EPB41L1. /evidence=ECO:0000269|PubMed:11136977	1..23
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..371
		PRK07764	<37..174	CDD:236090
		Interactions with HOMER1 and NF2	180..225
		Interaction with PLCG1. /evidence=ECO:0000269|PubMed:11823862	262..384
		G domain. /evidence=ECO:0000250	399..566
		Centaurin_gamma	401..560	CDD:133303
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	576..613
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	628..666
		PH_AGAP	668..908	CDD:241281
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..784
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	800..844
		ArfGap_AGAP	926..1033	CDD:350065	28/107 (26%)
		ANKYR	<1082..>1141	CDD:440430	9/61 (15%)
		ANK repeat	1084..1115	CDD:293786	5/33 (15%)
		ANK 1	1084..1113		5/31 (16%)
		ANK 2	1117..1146		6/28 (21%)
		ANK repeat	1117..1142	CDD:293786	5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1145..1174		8/28 (29%)