DRSC/TRiP Functional Genomics Resources

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Protein Alignment drongo and SMAP2

DIOPT Version :9

Sequence 1:NP_001162848.1 Gene:drongo / 33263 FlyBaseID:FBgn0020304 Length:673 Species:Drosophila melanogaster
Sequence 2:NP_073570.1 Gene:SMAP2 / 64744 HGNCID:25082 Length:429 Species:Homo sapiens


Alignment Length:412 Identity:92/412 - (22%)
Similarity:145/412 - (35%) Gaps:107/412 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 KQDDKYLLALRELVASGTGSNRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGL-TPPHRVKSIS 70
            |..|:|...|..|:..  ..|:.|.||..|||.:.:..||.|:|.||:|:.|.| ....||||::
Human     7 KDVDRYQAVLANLLLE--EDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVN 69

  Fly    71 MATFTQDEIDFLRSHGNELCAKTWLGLWDP------KRAVHQQEQRELMMDKYERKRYY------ 123
            :..:||::|..::..||....:    |::.      :|..........:.||||:|:|.      
Human    70 LDQWTQEQIQCMQEMGNGKANR----LYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDI 130

  Fly   124 ----------------------LEPA------SPLK----SLANAVNLKSSAP------------ 144
                                  |||.      .|.|    .|....:.||:||            
Human   131 NAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVA 195

  Fly   145 ---ATNHTQNGHQNGYASIHLTPPAAQRTSANGLQKVANS--SSNSSGKTSSSIS---RPHYNHQ 201
               |.:.|.|..:.....:...|    ..|::|.:||..|  ::.|:|....:::   .|....:
Human   196 CSIANSKTSNTLEKDLDLLASVP----SPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSKSE 256

  Fly   202 --NNSQNNNHDAFGLGGG-----------LSSLNSAGST---STGALSDTSSCASNGFGADCDFV 250
              ...|.:......|.|.           ::....|..|   |...::..:|...:........|
Human   257 EIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMV 321

  Fly   251 ADFGSANIFDATSARSTGSPAVSSVSSVGSSNGYAKVQ-----------PIRAAHLQQQQQLQQQ 304
            |..|::.:. |..|...|.......|.:|..||....|           |.....:|..||||..
Human   322 AQPGASGMV-APMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWN 385

  Fly   305 LHQ--QQL--LNGNGHQGTENF 322
            |.|  ||:  :|..|..|..|:
Human   386 LTQMTQQMAGMNFYGANGMMNY 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drongoNP_001162848.1 ArfGap 15..126 CDD:279720 36/145 (25%)
SMAP2NP_073570.1 ArfGap_SMAP2 16..122 CDD:350083 33/111 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 138..184 9/45 (20%)
Interaction with clathrin heavy chains. /evidence=ECO:0000250 163..232 15/72 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 217..259 9/45 (20%)
Interaction with PICALM. /evidence=ECO:0000250 340..429 19/68 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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