DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment drongo and agap3

DIOPT Version :9

Sequence 1:NP_001162848.1 Gene:drongo / 33263 FlyBaseID:FBgn0020304 Length:673 Species:Drosophila melanogaster
Sequence 2:XP_009295860.1 Gene:agap3 / 324332 ZFINID:ZDB-GENE-110927-1 Length:1295 Species:Danio rerio


Alignment Length:246 Identity:57/246 - (23%)
Similarity:95/246 - (38%) Gaps:60/246 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 NRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGL-TPPHRVKSISMATFTQDEIDFLRSHGNELC 90
            |..|.||....|.:.::.:|:.:|..|||:.|.| |...||:|:.:..:..:....:.:.||.:.
Zfish  1054 NSFCADCDAPNPDWASLNLGALICIECSGMHRNLGTHLSRVRSLDLDDWPVELSMVMTAIGNAMA 1118

  Fly    91 AKTWLGLWD----PKRAVHQQEQRELMMDKYERKRYYLE-PAS--PL-KSLANAV---NLK---- 140
            ...|....|    |.....::|:...:..|||:|.:.:. |.|  || :.|..||   :|:    
Zfish  1119 NSVWEACVDGYNKPGVDSTREEKERWIRAKYEQKLFVVALPQSDVPLGQQLLRAVVEDDLRLVVL 1183

  Fly   141 ----SSAPATNHTQNGHQNGYASIHL----------------------------TPPA-AQRTSA 172
                .:....|.|. |..:|..::||                            ||.: |||.  
Zfish  1184 LLAHGTKEEVNETY-GDGDGRTALHLSCAMANVVITQLLIWYGVDVKSRDARGQTPLSYAQRA-- 1245

  Fly   173 NGLQKVAN-SSSNSSGKTSSSISRPHYNHQNNSQNNNHDAFGLGGGLSSLN 222
             |.|:.|: ...:.......::|.|.....|.:.|||:      |..:.||
Zfish  1246 -GSQECADILIQHGCPAEGGALSTPTATRHNPNINNNN------GQCAELN 1289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drongoNP_001162848.1 ArfGap 15..126 CDD:279720 26/104 (25%)
agap3XP_009295860.1 small_GTPase 507..672 CDD:197466
Centaurin_gamma 509..666 CDD:133303
PH_AGAP 778..1025 CDD:241281
PH 781..>845 CDD:278594
ArfGap 1044..1155 CDD:279720 26/100 (26%)
Ank_2 1190..1259 CDD:289560 14/72 (19%)
ANK 1199..>1259 CDD:238125 11/62 (18%)
ANK repeat 1201..1232 CDD:293786 3/30 (10%)
ANK repeat 1234..1259 CDD:293786 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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