DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drongo and Agap1

DIOPT Version :9

Sequence 1:	NP_001162848.1	Gene:	drongo / 33263	FlyBaseID:	FBgn0020304	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	XP_038939665.1	Gene:	Agap1 / 316611	RGDID:	1309244	Length:	1428	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	54/237 - (22%)
Similarity:	95/237 - (40%)	Gaps:	63/237 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGL-TPPHRVKSISMATFTQDEIDFLRSHGNELC 90
            |..|.||..:.|.:.::.:|:.:|..|||:.|.| |...||:|:.:..:..:.|..:.|.||||.
  Rat  1192 NSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELA 1256

  Fly    91 AKTW----LGLWDPKRAVHQQEQRELMMDKYERKRYYLEP--------------ASPLKSLANAV 137
            ...|    .|...|.....::|:...:..|||:| .:|.|              |:..:.|...:
  Rat  1257 NSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQK-LFLAPLPCTEFSLGQQLLHATAEEDLRTVI 1320

  Fly   138 NL--KSSAPATNHTQNGHQNGYASIHLTPPAAQRTSA--------NGLQKVANSSSNSSGKTSSS 192
            .|  ..|....|.| .|..:|..::||   |.::.:.        .|:..:|.   ::.|.|:.:
  Rat  1321 LLLAHGSRDEVNET-CGEGDGRTALHL---ACRKGNVVLVQLLIWYGVDVMAR---DAHGNTALA 1378

  Fly   193 ISR--------------------------PHYNHQNNSQNNN 208
            .:|                          |:.:.:|||:||:
  Rat  1379 YARQASSQECIDVLLQYGCPDERFVLMATPNLSRKNNSRNNS 1420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drongo	NP_001162848.1	ArfGap	15..126	CDD:279720	31/103 (30%)
Agap1	XP_038939665.1	Centaurin_gamma	561..722	CDD:133303
		PH_AGAP	837..>911	CDD:241281
		PH-like	<1123..1163	CDD:418428
		ArfGap_AGAP2	1180..1288	CDD:350078	27/95 (28%)
		ANK repeat	1304..1332	CDD:293786	4/27 (15%)
		Ank_2	1307..1397	CDD:403870	16/96 (17%)
		ANK repeat	1339..1370	CDD:293786	6/36 (17%)
		ANK repeat	1372..1397	CDD:293786	3/24 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900