DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drongo and Agap3

DIOPT Version :9

Sequence 1:	NP_001162848.1	Gene:	drongo / 33263	FlyBaseID:	FBgn0020304	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	XP_006535736.1	Gene:	Agap3 / 213990	MGIID:	2183446	Length:	1093	Species:	Mus musculus

Alignment Length:	162	Identity:	44/162 - (27%)
Similarity:	73/162 - (45%)	Gaps:	23/162 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NRQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGLTPPH--RVKSISMATFTQDEIDFLRSHGNEL 89
            |..|.||....|.:.::.:|:.:|..|||:.|.| ..|  ||:|:.:..:..:.:..:.:.||.|
Mouse   856 NSLCIDCEAPNPDWASLNLGALMCIECSGIHRHL-GAHLSRVRSLDLDDWPPELLAVMTAMGNAL 919

  Fly    90 CAKTWLGLWD----PKRAVHQQEQRELMMDKYERKRYYLE-PAS--PL-KSLANAV---NLK--- 140
            ....|.|..|    |.....::|:...:..|||:|.:... |:|  || :.|..||   :|:
Mouse   920 ANSVWEGALDGYSKPGPEACREEKERWIRAKYEQKLFLAPLPSSDVPLGQQLLRAVVEDDLRLLV 984

  Fly   141 -----SSAPATNHTQNGHQNGYASIHLTPPAA 167
                 .|....|.|. |..:|..::||:...|
Mouse   985 MLLAHGSKEEVNETY-GDGDGRTALHLSSAMA 1015

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drongo	NP_001162848.1	ArfGap	15..126	CDD:279720	28/105 (27%)
Agap3	XP_006535736.1	Centaurin_gamma	310..467	CDD:133303
		PH_AGAP	583..827	CDD:241281
		PRK07003	<645..>756	CDD:235906
		ArfGap_AGAP3	843..952	CDD:350080	25/96 (26%)
		Ank_2	971..1061	CDD:372319	12/46 (26%)
		ANK repeat	971..1001	CDD:293786	7/30 (23%)
		ANK repeat	1003..1034	CDD:293786	4/13 (31%)
		ANK repeat	1036..1061	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900