Protein Alignment drongo and git-1

DIOPT Version :10

• Sequence 1: NP_001162848.1
• Gene: drongo / 33263
• FlyBaseID: FBgn0020304
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_509761.2
• Gene: git-1 / 181253
• WormBaseID: WBGene00008805
• Length: 670
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 102/580 - (17%)
• Similarity: 168/580 - (28%)
• Gaps: 206/580 - (35%)

  Fly    28 RQCFDCGQKGPTYVNMTIGSFVCTRCSGVLRGLTPP-HRVKSISMATFTQDEIDFLRSHGNELCA 91
            ::|.|||:|...:.::..|:.:|:.|......|.|. ..::.:..:.:.::.|..:.:.......
 Worm    16 KECDDCGKKEVEWASVKKGTVICSECFCFHSYLGPSVSYLRHLRKSAWDEEHIRLVHALNTSNTN 80

  Fly    92 KTW-LGLW------------DPKRAVHQQEQRELMMDKYERKRYYLEPASPLKSLANAVNLKSSA 143
            ..| ..|:            ||.   |.:||  .:.:|||:..:..:.... :.|.|::|.:..|
 Worm    81 MIWESALYEGSTKFQKPMAQDPS---HIKEQ--FVKEKYEKLTFQPKRGKD-EDLENSLNRQLIA 139

  Fly   144 PATNHTQNGHQNGYASIHLTPPAAQRTSANGLQKVANSSSNSSGKTSSSISRPHYNHQNNSQNNN 208
            .|        ::.:|.:.|      |..|.|..  .|.....:|.|:.     |...:..:.|..
 Worm   140 CA--------RSDFAHVTL------RLIALGAD--VNYPDPETGDTAL-----HVAAREGNSNQV 183

  Fly   209 HDAFGLGGGLSSLNSAGSTSTGALSDTSSCASNGFGADCDFVADFGSANIFDATSARSTGSPAVS 273
            ...|..|..:.:.|..|........|.      |.|.....:.:| ...:||..|......
 Worm   184 ELLFLYGADIMAPNREGMLPYILARDA------GHGQLSHRIYEF-FFYVFDRFSFFMCNR---- 237

  Fly   274 SVSSVGSSNGYAKVQPIRAAHLQQQQQLQQQLHQQQLLNGNGHQGTENFADFDHAPIYNAVAPPT 338
                             :|.|...|.....::.::|.|....          |.....:.:....
 Worm   238 -----------------KADHKNNQDFFIPEVTEKQFLTKTN----------DSRAAISVLPKGQ 275

  Fly   339 FNDWISDWSRRGFHDPFDDCDDSPPGARPPAPAPAPAQVPAVSSPLPTVREEPELAWNF--WEDE 401
            |               ||.|:|:..                     .|||.|.|:.||.  |
 Worm   276 F---------------FDLCEDAFD---------------------ETVRRENEVNWNMTKW--- 301

  Fly   402 MRIEAQEKESQTKQPELGYSFSISTTTPLSPSNPFLPYLVSEEQHRNHPEKP-------SFSYSL 459
                                    ..|...|:|.|||........||...:.       .|:..|
 Worm   302 ------------------------AKTAKGPTNLFLPPTPQMSAARNQRRQKLAKFTPIQFTILL 342

  Fly   460 FSSISNSSQEDQADDHEMNVLNANFHDFFTWSAPLQNGHTTSPPKGGNAA-------MAPSE--- 514
            ...|.:..:....|:                .||:     :.|||....:       |..||
 Worm   343 IDLIKDQKRRITGDN----------------PAPV-----SEPPKNMRKSNDTPLRIMKKSEYAD 386

  Fly   515 -DRYAAL--------------KDLDE-------QLRELKASESATET--PTPTSGNVQAT 550
             |..|.:              ..|||       :|.|:|...|:|||  .|.|..|.:.|
 Worm   387 YDEVAGISCSPISGIVPNSQANTLDESSSRVWDELLEMKERLSSTETMVVTLTKQNEELT 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drongo	NP_001162848.1	ArfGap_AGFG	15..123	CDD:350067	21/108 (19%)
git-1	NP_509761.2	ArfGap	7..127	CDD:214518	21/116 (18%)
		ANKYR	<122..>212	CDD:440430	20/117 (17%)
		ANK repeat	165..197	CDD:293786	6/36 (17%)
		GIT	264..294	CDD:128828	9/65 (14%)
		GIT	326..356	CDD:128828	3/29 (10%)
		GIT1_C	570..669	CDD:463492