DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dock and grapb

DIOPT Version :9

Sequence 1:	NP_001259845.1	Gene:	dock / 33262	FlyBaseID:	FBgn0010583	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001025251.2	Gene:	grapb / 555184	ZFINID:	ZDB-GENE-050913-4	Length:	214	Species:	Danio rerio

Alignment Length:	194	Identity:	53/194 - (27%)
Similarity:	78/194 - (40%)	Gaps:	64/194 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 ALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRNA 395
            |||||.:....||||:||:.|::.:.. .||:||.| ...|:.|.||:||:
Zfish     5 ALYSFRATECDELSFQKGEILKVTNMD-DDPNWYTA-ELLGRRGYVPKNYI-------------- 53

  Fly   396 SASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDT 460
                                                          |:...:|:.|.|:|...:.
Zfish    54 ----------------------------------------------NVRPHTWFVGGISRQAAEN 72

  Fly   461 VLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVE-QNMYCIGQRKFHSLDQLVDHYQ 523
            .|... ..|.||||:||:..|::|||:......:||:|..: ...|.|....|.||:||||.|:
Zfish    73 RLRPL-ECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLGQYFIWDEVFSSLNQLVDFYR 135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_001259845.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700
		SH3_Nck_3	328..383	CDD:212701	23/51 (45%)
		SH2_Nck_family	446..538	CDD:198196	29/79 (37%)
grapb	NP_001025251.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582187
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840