Protein Alignment dock and grap2a

DIOPT Version :10

• Sequence 1: NP_722657.1
• Gene: dock / 33262
• FlyBaseID: FBgn0010583
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001017756.1
• Gene: grap2a / 550452
• ZFINID: ZDB-GENE-050417-275
• Length: 284
• Species: Danio rerio
• Alignment Length: 302
• Identity: 72/302 - (23%)
• Similarity: 106/302 - (35%)
• Gaps: 98/302 - (32%)

  Fly   158 KYDYAAQGAQELDLRKNERYLLLDDSKHWWRVQNSRNQSGYVPSNYVKKEKPSLFDSIKKKVKKG 222
            |||::.....||..||.:...:|.....|::.: .....||||.|||.::.||.|   |:...:|
Zfish     6 KYDFSGTAEDELSFRKGDTLKILGSQDDWFKAE-LHGHEGYVPKNYVDRQIPSWF---KESASRG 66

  Fly   223 SGSKTL------------PNCSP------------------------------------------ 233
            |..:||            ...||
Zfish    67 SAEETLMSREVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYYLWTEKFTSLNKLVDF 131

  Fly   234 ------SRQVE------------SPTMSRRLP---PDPAEAIGTAVVKYNYQAQQPDELSLTKGT 277
                  |:|.|            :|...:..|   |.|....|:.... :......|.....||.
Zfish   132 YKTTSISKQKEIFLRDGSGDEPRAPPPIKSQPEVRPPPGGGYGSPQTS-SQNRSTTDPTHNQKGK 195

  Fly   278 RILILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDNDGEIHTYAMAENVLDIVVALYSFTSNNDQE 342
            |..:.||||....:|::.      |:...|.:.         |.|......|.|:|.||:..|.|
Zfish   196 RGSVEEKSNTLGHQGKNS------PAPRRTSET---------APAPRSTIQVRAIYDFTAEEDDE 245

  Fly   343 LSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQEL 384
            |.|..||.:|::||  ||..|:|.| .:|:.||.|.||.:::
Zfish   246 LGFNSGDIIEVLDR--SDASWWKGR-LRGRSGLFPANYTEQI 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_722657.1	SH3_Nck_1	154..204	CDD:212699	14/45 (31%)
		SH3_Nck_2	256..308	CDD:212700	10/51 (20%)
		SH3_Nck_3	328..383	CDD:212701	25/54 (46%)
		SH2_Nck_family	446..538	CDD:198196
grap2a	NP_001017756.1	SH3_GRAP2_N	2..53	CDD:212880	16/47 (34%)
		SH2_Grb2_like	54..147	CDD:199828	13/95 (14%)
		SH3_GRAP2_C	231..283	CDD:212883	25/54 (46%)