Protein Alignment dock and nck1

DIOPT Version :9

• Sequence 1: NP_001259845.1
• Gene: dock / 33262
• FlyBaseID: FBgn0010583
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001008101.1
• Gene: nck1 / 493463
• XenbaseID: XB-GENE-6085807
• Length: 377
• Species: Xenopus tropicalis
• Alignment Length: 404
• Identity: 177/404 - (43%)
• Similarity: 257/404 - (63%)
• Gaps: 51/404 - (12%)

  Fly   155 VVAKYDYAAQGAQELDLRKNERYLLLDDSKHWWRVQNSRNQSGYVPSNYVKKEKPSLFDSIKKKV 219
            ||||:||.||..||||::||||..||||||.||||:||.|::|:||||||:::..:...||.|.:
 Frog     8 VVAKFDYVAQQDQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNL 72

  Fly   220 KKGSGSKTLPNCSPSRQVESPTMSRRLPPDPAEAI----GTAVVKYNYQAQQPDELSLTKGTRIL 280
            |...|...:.. .||....:.|....||  .||.:    ..|.||:.|.|::.|||||.|||:::
 Frog    73 KDTLGIGKVKR-KPSMPDSASTADDSLP--DAERLYDLNMPAYVKFTYTAERDDELSLVKGTKVI 134

  Fly   281 ILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDNDG--EIHTY-----AMAENV-----LDIVVALY 333
            ::||.:||||||.....||||||||.||:.|:..  ::.|.     |:..|:     |.:|.|||
 Frog   135 VMEKCSDGWWRGSYNGRVGWFPSNYVTEENDSPSGDQVGTLTEKLAAVVNNLNNGRSLHVVQALY 199

  Fly   334 SFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRNASAS 398
            .|:|:|::||:||||:.::::::|.:||:|:|.|.:.|.|||||:||:..:.::..||
 Frog   200 PFSSSNEEELNFEKGEVMDVIEKPENDPEWWKCRKSNGLVGLVPKNYVTIMQNFQPTP------- 257

  Fly   399 AGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLN 463
                             ..:.:..|.:...|:|  ||:      .||..||||.:||.|.:..||
 Frog   258 -----------------SFEPLPPRCDYIGPSA--SGR------FAGNQWYYGKVTRHQAEMALN 297

  Fly   464 GHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQRKFHSLDQLVDHYQRAPIY 528
            ..|::|||||||||::..|:||||||.|:||||:|.::..|||||||||.::::||:||::|||:
 Frog   298 ERGNEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQMKDCMYCIGQRKFSTMEELVEHYKKAPIF 362

  Fly   529 TNKQGEKLYLVRSL 542
            |::|||||||::.|
 Frog   363 TSEQGEKLYLIKPL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_001259845.1	SH3_Nck_1	154..204	CDD:212699	34/48 (71%)
		SH3_Nck_2	256..308	CDD:212700	29/51 (57%)
		SH3_Nck_3	328..383	CDD:212701	27/54 (50%)
		SH2_Nck_family	446..538	CDD:198196	54/91 (59%)
nck1	NP_001008101.1	SH3_Nck1_1	4..62	CDD:212833	36/53 (68%)
		SH3_Nck1_2	108..162	CDD:212834	29/53 (55%)
		SH3_Nck1_3	193..249	CDD:212837	27/55 (49%)
		SH2_Nck1	280..376	CDD:198271	56/95 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I6426
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38148
Inparanoid	1	1.050	333	1.000	Inparanoid score	I2377
OMA	1	1.010	-	-		QHG46567
OrthoDB	1	1.010	-	-		D1097449at2759
OrthoFinder	1	1.000	-	-		FOG0002240
OrthoInspector	1	1.000	-	-		otm47582
Panther	1	1.100	-	-	LDO	PTHR19969
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4150
SonicParanoid	1	1.000	-	-		X1672
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110