DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dock and Grap

DIOPT Version :9

Sequence 1:	NP_001259845.1	Gene:	dock / 33262	FlyBaseID:	FBgn0010583	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001020920.1	Gene:	Grap / 363616	RGDID:	1306884	Length:	217	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	59/204 - (28%)
Similarity:	88/204 - (43%)	Gaps:	63/204 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 VALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRN 394
            ||||:|.:....||:|.|||.|:|::.. .|.:|||| ..:|..|.||:||::.
  Rat     4 VALYNFQATESDELAFNKGDTLKILNMD-DDQNWYKA-ELRGAEGFVPKNYIRV----------- 55

  Fly   395 ASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCD 459
                                             ||                ..||.|.|:|...:
  Rat    56 ---------------------------------KP----------------HPWYSGRISRQLAE 71

  Fly   460 TVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVE-QNMYCIGQRKFHSLDQLVDHYQ 523
            ..|....|.|.||||:||::.|::|||:....:.:||:|..| ...|.:.:.||:||::|||.|:
  Rat    72 ETLMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYR 136

  Fly   524 RAPIYTNKQ 532
            ...|...:|
  Rat   137 TTTIAKRRQ 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_001259845.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700
		SH3_Nck_3	328..383	CDD:212701	24/52 (46%)
		SH2_Nck_family	446..538	CDD:198196	33/88 (38%)
Grap	NP_001020920.1	SH3_GRAP_N	2..55	CDD:212881	24/52 (46%)
		SH2_Grb2_like	56..150	CDD:199828	35/106 (33%)
		SH3	162..214	CDD:418401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342147
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840