Protein Alignment dock and yrk

DIOPT Version :10

• Sequence 1: NP_722657.1
• Gene: dock / 33262
• FlyBaseID: FBgn0010583
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001352482.1
• Gene: yrk / 337571
• ZFINID: ZDB-GENE-030131-9517
• Length: 528
• Species: Danio rerio
• Alignment Length: 328
• Identity: 72/328 - (21%)
• Similarity: 122/328 - (37%)
• Gaps: 130/328 - (39%)

  Fly   220 KKGSGSKTLPN---C---------SPSRQVESPTMSRRLPPDPAEAIGTAVVKYNYQAQQPDELS 272
            |:...||.:.|   |         .|||.:..||.:..:|            .:| ....|
Zfish     7 KQRKASKAVSNQNSCDAFNGTQASEPSRYIPDPTFNSGIP------------NFN-DFSNP---- 54

  Fly   273 LTKGTRILILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDNDGEIHTYAMAENVLDIVVALYSFTS 337
            ||..|.|:     |.....|.:|..|..|                            :|||.:.:
Zfish    55 LTPPTSII-----NPARPPGLTGGGVTLF----------------------------IALYEYDA 86

  Fly   338 NNDQELSFEKGDRLEIVDRPASDPDWYKARN-NQGQVGLVPRNYLQELNDYLATPYRNASASAGN 401
            ..:.:|||:||::..|::.  ::.||::||: :.|:.|.:|.||:
Zfish    87 RTEDDLSFQKGEKFHIINN--TEGDWWEARSLDTGKSGYIPSNYV-------------------- 129

  Fly   402 GNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHG 466
                                              .|::  ::..:.||:|.:.|...:..|....
Zfish   130 ----------------------------------APVD--SIQAEEWYFGKMGRKDAERQLLAQN 158

  Fly   467 HD-GDFLIRDSETNMGDYSVSLK----APGRN-KHFRVHVEQN--MYCIGQRKFHSLDQLVDHY- 522
            :. |.||||:|||..|.||:|::    |.|.: ||:::....|  .|...:.:|.::.|||:||
Zfish   159 NPRGTFLIRESETTKGAYSLSIRDWDDAKGDHVKHYKIRKLDNGGYYITTRTQFDTVQQLVEHYT 223

  Fly   523 QRA 525
            :||
Zfish   224 ERA 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_722657.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700	11/51 (22%)
		SH3_Nck_3	328..383	CDD:212701	18/55 (33%)
		SH2_Nck_family	446..538	CDD:198196	31/89 (35%)
yrk	NP_001352482.1	SH3	76..133	CDD:473055	20/140 (14%)
		SH2	136..234	CDD:472789	31/91 (34%)
		PTKc_Src_Fyn_like	266..513	CDD:271105