Protein Alignment dock and Nck1

DIOPT Version :9

• Sequence 1: NP_001259845.1
• Gene: dock / 33262
• FlyBaseID: FBgn0010583
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001100321.1
• Gene: Nck1 / 300955
• RGDID: 1310688
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 414
• Identity: 179/414 - (43%)
• Similarity: 254/414 - (61%)
• Gaps: 70/414 - (16%)

  Fly   155 VVAKYDYAAQGAQELDLRKNERYLLLDDSKHWWRVQNSRNQSGYVPSNYVKKEKPSLFDSIKKKV 219
            ||||:||.||..||||::||||..||||||.||||:||.|::|:||||||:::..:...||.|.:
  Rat     7 VVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNL 71

  Fly   220 KKGSGSKTLPNCSPSRQVESPTMSRRLPP------DPAEAI----GTAVVKYNYQAQQPDELSLT 274
            |...|.        .:....|::.....|      ||.|.:    ..|.||:||.|::.|||||.
  Rat    72 KDTLGI--------GKVKRKPSVPDTASPADDSFVDPGERLYDLNMPAFVKFNYMAEREDELSLI 128

  Fly   275 KGTRILILEKSNDGWWRGQSGNSVGWFPSNYTTEDCDNDGEIHTYAMAE------------NVLD 327
            |||:::::||.:||||||.....:|||||||.||:.|:....|..:::|            .||.
  Rat   129 KGTKVIVMEKCSDGWWRGSYNGQIGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLH 193

  Fly   328 IVVALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPY 392
            :|.|||.|:|:||:||:|||||.::::::|.:||:|:|.|...|.|||||:||:        |..
  Rat   194 VVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYV--------TVM 250

  Fly   393 RNASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGK----SWYYGAI 453
            :|...::|                       .|.:.|...     ..||:|.||    .||||.:
  Rat   251 QNNPLTSG-----------------------LEPSPPQCD-----YIRPSLTGKFAGNPWYYGKV 287

  Fly   454 TRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQNMYCIGQRKFHSLDQL 518
            ||.|.:..||..||:|||||||||::..|:||||||.|:||||:|.:::.:||||||||.::::|
  Rat   288 TRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEEL 352

  Fly   519 VDHYQRAPIYTNKQGEKLYLVRSL 542
            |:||::|||:|::||||||||:.|
  Rat   353 VEHYKKAPIFTSEQGEKLYLVKHL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_001259845.1	SH3_Nck_1	154..204	CDD:212699	34/48 (71%)
		SH3_Nck_2	256..308	CDD:212700	29/51 (57%)
		SH3_Nck_3	328..383	CDD:212701	29/54 (54%)
		SH2_Nck_family	446..538	CDD:198196	55/95 (58%)
Nck1	NP_001100321.1	SH3_Nck1_1	3..61	CDD:212833	36/53 (68%)
		SH3_Nck1_2	108..162	CDD:212834	29/53 (55%)
		SH3_Nck1_3	193..249	CDD:212837	29/63 (46%)
		SH2_Nck1	280..376	CDD:198271	57/95 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I6172
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38148
Inparanoid	1	1.050	333	1.000	Inparanoid score	I2332
OMA	1	1.010	-	-		QHG46567
OrthoDB	1	1.010	-	-		D1097449at2759
OrthoFinder	1	1.000	-	-		FOG0002240
OrthoInspector	1	1.000	-	-		otm44545
orthoMCL	1	0.900	-	-		OOG6_106243
Panther	1	1.100	-	-	LDO	PTHR19969
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1672
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980