Protein Alignment dock and Yes1

DIOPT Version :10

• Sequence 1: NP_722657.1
• Gene: dock / 33262
• FlyBaseID: FBgn0010583
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_033561.1
• Gene: Yes1 / 22612
• MGIID: 99147
• Length: 541
• Species: Mus musculus
• Alignment Length: 309
• Identity: 65/309 - (21%)
• Similarity: 123/309 - (39%)
• Gaps: 90/309 - (29%)

  Fly   231 CSPSRQVESPTMSRRLPPDPAEAIGTAVVKYNYQAQQPDELSLTKGTRILILEKSNDGWWRGQSG 295
            |..|::.:||.: :..|.:..|.:..:...|..:.......|.|||..:              :.
Mouse     3 CIKSKENKSPAI-KYTPENLTEPVSPSASHYGVEHATVAPTSSTKGASV--------------NF 52

  Fly   296 NSVGWFPSNYTTEDCDNDGEIHTYAMAENV--------LDIVVALYSFTSNNDQELSFEKGDRLE 352
            ||:...|...::......|...::::..:.        :.|.||||.:.:...::|||:||:|.:
Mouse    53 NSLSMTPFGGSSGVTPFGGASSSFSVVSSSYPTGLTGGVTIFVALYDYEARTTEDLSFKKGERFQ 117

  Fly   353 IVDRPASDPDWYKARN-NQGQVGLVPRNYLQELNDYLATPYRNASASAGNGNGGGSNGGAGGGGG 416
            |::.  ::.||::||: ..|:.|.:|.||:
Mouse   118 IINN--TEGDWWEARSIATGKSGYIPSNYV----------------------------------- 145

  Fly   417 NDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDTVLNGHGHD-GDFLIRDSETNM 480
                                 :...::..:.||:|.:.|...:.:|...|:. |.||:|:|||..
Mouse   146 ---------------------VPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTK 189

  Fly   481 GDYSVSLK----APGRN-KHFRVHVEQN--MYCIGQRKFHSLDQLVDHY 522
            |.||:|::    ..|.| ||:::....|  .|...:.:|.:|.:||.||
Mouse   190 GAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHY 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_722657.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700	8/51 (16%)
		SH3_Nck_3	328..383	CDD:212701	21/55 (38%)
		SH2_Nck_family	446..538	CDD:198196	29/85 (34%)
Yes1	NP_033561.1	SH3_Yes	92..149	CDD:212940	21/114 (18%)
		SH2_Src_family	152..251	CDD:199827	29/87 (33%)
		PTKc_Yes	262..540	CDD:270654