Protein Alignment dock and src-1

DIOPT Version :10

• Sequence 1: NP_722657.1
• Gene: dock / 33262
• FlyBaseID: FBgn0010583
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001364829.1
• Gene: src-1 / 171722
• WormBaseID: WBGene00005077
• Length: 537
• Species: Caenorhabditis elegans
• Alignment Length: 289
• Identity: 68/289 - (23%)
• Similarity: 113/289 - (39%)
• Gaps: 102/289 - (35%)

  Fly   258 VVKYNYQAQQPDELSL-------TKGTRILILEKSNDGWW-RGQSGNSVGWFPSNYTTEDCDNDG 314
            |.:|..:.|.|.:.::       .:|| |..|..::||.. .|:.|...|......|
 Worm    24 VSRYPRRFQTPQQQTVFHVNNGGNEGT-ISQLNGTSDGMMGNGRGGGGGGGAQERET-------- 79

  Fly   315 EIHTYAMAENVLDIVVALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQ-GQVGLVPR 378
                          :||||.:.|..|.:|||:|||.:.::|.  |:.||:..|:.: ||.|.|||
 Worm    80 --------------LVALYPYDSRADGDLSFQKGDAMYLLDH--SNCDWWYVRHQRTGQTGYVPR 128

  Fly   379 NYLQELNDYLATPYRNASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNL 443
            |::                                                   :..|.||
 Worm   129 NFV---------------------------------------------------AKQQTIE---- 138

  Fly   444 AGKSWYYGAITRSQCD-TVLNGHGHDGDFLIRDSETNMGDYSVSLKAP------GRNKHFRV--- 498
             .:.||.|.|.|::.: .||:.|...|.||||:.|.:..:::::::..      |..||:::
 Worm   139 -SEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRL 202

  Fly   499 -HVEQNMYCIGQRKFHSLDQLVDHYQRAP 526
             | :|..:...:|.|.||.:||.:|...|
 Worm   203 DH-DQGYFITTRRTFRSLQELVRYYSDVP 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_722657.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700	14/57 (25%)
		SH3_Nck_3	328..383	CDD:212701	24/55 (44%)
		SH2_Nck_family	446..538	CDD:198196	27/92 (29%)
src-1	NP_001364829.1	SH3_Src_like	79..130	CDD:212779	24/74 (32%)
		SH2_Src_family	138..240	CDD:199827	28/99 (28%)
		PTKc_Src_like	270..522	CDD:270630