DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dock and grap

DIOPT Version :9

Sequence 1:	NP_001259845.1	Gene:	dock / 33262	FlyBaseID:	FBgn0010583	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001332868.1	Gene:	grap / 100127598	XenbaseID:	XB-GENE-6258733	Length:	219	Species:	Xenopus tropicalis

Alignment Length:	200	Identity:	55/200 - (27%)
Similarity:	87/200 - (43%)	Gaps:	65/200 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 ALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRNA 395
            |:|:|.:....||.|:|||.::|::. ..|.:|:|| ...|:.|.:|:||::.
Frog     5 AIYNFKTTERDELPFKKGDIIKILNM-EDDQNWFKA-ELFGREGYIPKNYIKV------------ 55

  Fly   396 SASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCDT 460
                                            ||                ..||.|.|:|...:.
Frog    56 --------------------------------KP----------------HPWYAGRISRQVAEE 72

  Fly   461 VLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRV--HVEQN-MYCIGQRKFHSLDQLVDHY 522
            :|......|.|||||||::.||:|:|:......:||:|  ..|.| .|.:.:.||:||::|||:|
Frog    73 ILLKRNFVGAFLIRDSESSPGDFSISVNYGHHVQHFKVLRDTESNGKYYLWEAKFNSLNELVDYY 137

  Fly   523 QRAPI 527
            :|..|
Frog   138 RRHSI 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dock	NP_001259845.1	SH3_Nck_1	154..204	CDD:212699
		SH3_Nck_2	256..308	CDD:212700
		SH3_Nck_3	328..383	CDD:212701	19/51 (37%)
		SH2_Nck_family	446..538	CDD:198196	33/84 (39%)
grap	NP_001332868.1	SH3_GRAP_N	2..55	CDD:212881	19/51 (37%)
		SH2_Grb2_like	56..152	CDD:199828	35/102 (34%)
		SH3_GRAP_C	161..213	CDD:212884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910