DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and AT1G69710

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_177129.2	Gene:	AT1G69710 / 843307	AraportID:	AT1G69710	Length:	1041	Species:	Arabidopsis thaliana

Alignment Length:	467	Identity:	111/467 - (23%)
Similarity:	189/467 - (40%)	Gaps:	99/467 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DKSKIKEYSPKTTDSH--EHR-------VYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRLQF 82
            |..::...|..:|.||  .|.       |:|||  |:.:.|:.:....:....||....|..|:.
plant   234 DPFRLSLSSAVSTSSHGSYHEDFDALGDVFVWG--ESISDGVLSGTGNSLNSTTEDALLPKALES 296

  Fly    83 SNNNEITDVAAGYGFTVYAVNRDD----GE---TLFGSGLNTDSQLGFQVKGNPNDPANLDVIIY 140
            :...:..::|.|....|....:.:    ||   ...|.||.||:|                   .
plant   297 TIVLDAQNIACGKCHAVLVTKQGEIFSWGEGKGGKLGHGLETDAQ-------------------K 342

  Fly   141 PTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALI 205
            |..|...|..|       .||::.|..|...:||:|.:::.|:.::..   .::.....|...:.
plant   343 PKFISSVRGLG-------FKSLACGDFHTCAITQSGDLYSWGDGTHNV---DLLGHGNESSCWIP 397

  Fly   206 HRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEK 270
            .|:: .|:.|.  .|..|.||..|:..:...|:::|.|.|..|..|.|:..:    |.:..:||.
plant   398 KRVT-GDLQGL--YVSDVACGPWHTAVVASSGQLFTFGDGTFGALGHGDRRS----TSVPREVES 455

  Fly   271 ---EKIVRLSC----SSDCVLALNEA---------GDAFGWGNSEYGQLDDSELAETQINIPRAL 319
               ..:.:::|    ::..|...|||         |..|.||:.|.|||...: .:|::.....:
plant   456 LIGLIVTKVACGVWHTAAVVEVTNEASEAEVDSSRGQVFTWGDGEKGQLGHGD-NDTKLLPECVI 519

  Fly   320 KLTKSIGKIKDVAAGGSFCMALNDQGLVYTWG---FGILGFGPFVEQTSK---PQHLLPPLFGRN 378
            .||..  .|..||.|.|..::...:|.|||.|   :|.||     ..|:|   |:.:...:.
plant   520 SLTNE--NICQVACGHSLTVSRTSRGHVYTMGSTAYGQLG-----NPTAKGNFPERVEGDIV--- 574

  Fly   379 DFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKAAING-----KVTK 438
                |.:|..|.||.:|:..:.|..:::.|||...|.||.|:.:::..|   |:.|     :|..
plant   575 ----EASVEEIACGSYHVAVLTSKSEIYTWGKGLNGQLGHGNVENKREP---AVVGFLREKQVKA 632

  Fly   439 VAYGVDHTIALC 450
            :..|.:.|..:|
plant   633 ITCGSNFTAVIC 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	13/62 (21%)
		RCC1_2	159..188	CDD:290274	8/28 (29%)
		RCC1	175..233	CDD:278826	11/57 (19%)
		RCC1_2	220..249	CDD:290274	9/28 (32%)
		RCC1	236..286	CDD:278826	12/56 (21%)
		RCC1	290..341	CDD:278826	16/50 (32%)
		RCC1	345..395	CDD:278826	16/55 (29%)
		RCC1_2	386..414	CDD:290274	9/27 (33%)
		RCC1	402..449	CDD:278826	13/51 (25%)
AT1G69710	NP_177129.2	PH_PLC_plant-like	25..135	CDD:270171
		RCC1_2	354..381	CDD:290274	8/26 (31%)
		RCC1	370..422	CDD:278826	11/57 (19%)
		RCC1	425..474	CDD:278826	11/52 (21%)
		RCC1	491..537	CDD:278826	16/48 (33%)
		RCC1	543..591	CDD:278826	17/59 (29%)
		RCC1	596..643	CDD:278826	13/49 (27%)
		FYVE	646..714	CDD:214499
		DUF4200	838..936	CDD:290574
		BRX_N	896..>921	CDD:290432
		BRX	981..1035	CDD:285568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910