DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and RUG3

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_974971.2	Gene:	RUG3 / 836208	AraportID:	AT5G60870	Length:	452	Species:	Arabidopsis thaliana

Alignment Length:	494	Identity:	112/494 - (22%)
Similarity:	185/494 - (37%)	Gaps:	112/494 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RSYTAK-------AKRGVLAQDKSKIKEYSPK-TTDSHEHRVYVWGFQETGALG----------- 58
            ||:|.:       .:.|..|..|..|...||. .:|....:::.||...:|.||
plant     9 RSFTRRFSSTRTTQRSGGGANTKVPILYTSPDIDSDPVTLQLFSWGRGASGQLGGGIEEIRMYPS 73

  Fly    59 LQTNVKKAKERYTEMVHHPTRLQFSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGF 123
            ...|:....::...:...|.|:...:::....::.|               ||.|||..|..|..
plant    74 PVANLLFRSDQSFSLAQTPGRIDADSSSFRIGISCG---------------LFHSGLTIDGDLWI 123

  Fly   124 QVKGNPNDPANL-----DVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGN 183
            ..||   |...|     :.:..|....|       .|:..::.::.|..|.|.||..|.:||.|.
plant   124 WGKG---DGGRLGFGQENSVFVPNLNPL-------FEEHSIRCIALGGLHSVALTHQGDVFTWGY 178

  Fly   184 NSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWG--- 245
            ..:|..|..:     |::..:..|:.....|    ::..:.....|:..:|:.|.:|.  ||
plant   179 GGFGALGHKV-----YTRELVPRRVDDSWDC----KISAIATSGTHTAAITESGELYM--WGREE 232

  Fly   246 ADGQTGQGNYHTAGQITLIGGDV---EKEK-----IVRLSCSSDCVLALNEAGDAFGWG---NSE 299
            .||:.|.|    .|:....||.:   .|.|     :..:||.....:||.:.|..:.||   |.|
plant   233 GDGRLGLG----PGRGPNEGGGLSVPSKVKALTVPVASVSCGGFFTMALTKEGQLWNWGANSNYE 293

  Fly   300 YGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQT 364
            .|:.|:....|     |..:...:.: :|..:|.||...:||.::|.|.:||.|  |.|.....:
plant   294 LGRGDNLGGWE-----PMPVPSLEGV-RITQIACGGYHSLALTEEGKVLSWGHG--GHGQLGSSS 350

  Fly   365 SKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAV-------NSDGDLFMWGKNRFGHLGL-GHK 421
            .:.|.:...:....|    ..:|.|..|.....|:       ...|:|:|||..:...||: |..
plant   351 LRNQKVPTEIEALAD----KKIVFIASGGSSSAAITGWDWFLTDGGELWMWGNAKDFQLGVPGLP 411

  Fly   422 KDQFFPFKAAIN----------GKVTKVAYGVDHTIALC 450
            :.|..|.:  :|          .||..::.|..|  |||
plant   412 EIQTTPVE--VNFLTEEDECQPHKVISISIGASH--ALC 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	9/66 (14%)
		RCC1_2	159..188	CDD:290274	9/28 (32%)
		RCC1	175..233	CDD:278826	10/57 (18%)
		RCC1_2	220..249	CDD:290274	7/31 (23%)
		RCC1	236..286	CDD:278826	15/60 (25%)
		RCC1	290..341	CDD:278826	13/53 (25%)
		RCC1	345..395	CDD:278826	12/49 (24%)
		RCC1_2	386..414	CDD:290274	9/34 (26%)
		RCC1	402..449	CDD:278826	15/57 (26%)
RUG3	NP_974971.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910