DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and AT5G42140

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001318728.1	Gene:	AT5G42140 / 834219	AraportID:	AT5G42140	Length:	1078	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	115/486 - (23%)
Similarity:	185/486 - (38%)	Gaps:	104/486 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RSYTAKAKRGVLAQ----DKSKIKEYSPKTTDSHEHR---------VYVWG---FQETGALGLQT 61
            ||:.|.....:|.:    |..::...|.:::.||...         ||:||   .:.....|...
plant   190 RSHVASDSPNMLVRGTGSDAFRVSVSSVQSSSSHGSAPDDCDALGDVYIWGEVLCENVTKFGADK 254

  Fly    62 NVKKAKERYTEMVHHPTRLQFSNNNEITDV---AAGYGFTVYAVNRDDGETLFGSGLNTDSQLGF 123
            |:.....|...::..|.     .:|.:.||   |.|..... .|:| .|| :|..|..:..:||.
plant   255 NIGYLGSRSDVLIPKPL-----ESNVVLDVHHIACGVKHAA-LVSR-QGE-VFTWGEASGGRLGH 311

  Fly   124 QVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSY-- 186
            .:..:...|..::.:            ..|..|.    ::.|..|...:|..|.|:|.|:.::
plant   312 GMGKDVTGPQLIESL------------AATSIDF----VACGEFHTCAVTMTGEIYTWGDGTHNA 360

  Fly   187 GQCGRSIIEEERYSKSALIHRISQEDICGKED--EVVQVECGQDHSMFLTKKGRIYTCGWGADGQ 249
            |..|..         :.:.|.|.:. |.|..:  ::..|.||..|:..:|..|:::|.|.|..|.
plant   361 GLLGHG---------TDVSHWIPKR-ISGPLEGLQIASVSCGPWHTALITSTGQLFTFGDGTFGV 415

  Fly   250 TGQGNYHTA---GQITLIGGDVEKEKIVRLSCSSDCVLALNE-----------AGDAFGWGNSEY 300
            .|.|:..|.   .::..:.|    .:.:.::|......|:.|           :|..|.||:.:.
plant   416 LGHGDKETVFYPREVESLSG----LRTIAVACGVWHAAAIVEVIVTHSSSSVSSGKLFTWGDGDK 476

  Fly   301 GQL--DDSELAETQINIPRALKLTKSIGKIKD-----VAAGGSFCMALNDQGLVYTWGFGILGFG 358
            .:|  .|.|        || ||.| .:..:.|     ||.|.|..:.|...|.|||.|..:.|
plant   477 SRLGHGDKE--------PR-LKPT-CVSALIDHTFHRVACGHSLTVGLTTSGKVYTMGSTVYG-- 529

  Fly   359 PFVEQTSKP--QHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHK 421
                |...|  ...||.|.  .|...:..|..|.||.:|:..:.|..::|.|||...|.||.|..
plant   530 ----QLGNPNADGKLPCLV--EDKLTKDCVEEIACGAYHVAVLTSRNEVFTWGKGANGRLGHGDV 588

  Fly   422 KDQFFP--FKAAINGKVTKVAYGVDHTIALC 450
            :|:..|  ..|.....|..:|.|.:.|.|:|
plant   589 EDRKAPTLVDALKERHVKNIACGSNFTAAIC 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	13/70 (19%)
		RCC1_2	159..188	CDD:290274	7/30 (23%)
		RCC1	175..233	CDD:278826	14/61 (23%)
		RCC1_2	220..249	CDD:290274	9/28 (32%)
		RCC1	236..286	CDD:278826	10/52 (19%)
		RCC1	290..341	CDD:278826	17/57 (30%)
		RCC1	345..395	CDD:278826	16/51 (31%)
		RCC1_2	386..414	CDD:290274	10/27 (37%)
		RCC1	402..449	CDD:278826	15/48 (31%)
AT5G42140	NP_001318728.1	PH_PLC_plant-like	12..124	CDD:270171
		ATS1	<282..614	CDD:227511	93/382 (24%)
		FYVE	621..689	CDD:214499
		BRX_N	869..904	CDD:372684
		BRX	1003..1057	CDD:369842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910