DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3862 and AT3G03790

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001189802.1	Gene:	AT3G03790 / 821145	AraportID:	AT3G03790	Length:	1099	Species:	Arabidopsis thaliana

Alignment Length:	427	Identity:	88/427 - (20%)
Similarity:	150/427 - (35%)	Gaps:	150/427 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VYVWGFQETGALGLQTNVKKAKERYTEMVHHPTRLQFSNNNEITDVAAGYGFTVYAVNRDDGETL 110
            ||.|||...|.||                 ||   :|       |:.:|....:     ...:.:
plant   207 VYTWGFGRGGRLG-----------------HP---EF-------DIHSGQAAVI-----TPRQVI 239

  Fly   111 FGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQN 175
            .|.|                                         ..|||:::|.:.|.|:.|:.
plant   240 SGLG-----------------------------------------SRRVKAVAAAKHHTVIATEG 263

  Fly   176 GTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIY 240
            |.::|.|:|..||.|.:.::.:          .:...:...:.::|.|.....|:..::..|.::
plant   264 GDVYTWGSNREGQLGYTSVDTQ----------ATPRKVTSLKAKIVAVSAANKHTAVVSDCGEVF 318

  Fly   241 TCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRLSCSSDC-VLALNEAGDAFGWGNSEYGQLD 304
            |.|...:||.|.|..::|...:....|..|.|:.....||.. .|.|...|:.:.||:
plant   319 TWGCNKEGQLGYGTSNSASNYSPRLVDYLKGKVFTAIASSKYHTLVLRNDGEVYTWGH------- 376

  Fly   305 DSELAETQINIPRALKLTKSIGK---------------IKDVAAGGSFCMALNDQGLVYTWGFGI 354
                   ::..||.:.:::::.|               :..:|||....:||.:.|..:.|
plant   377 -------RLVTPRRVIISRNLKKAGNTLLNFHRRRPLRLTAIAAGMVHSLALAEDGAFFYW---- 430

  Fly   355 LGFGPFVEQTSKPQHL----LPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMW-GKNRFG 414
                     .|...:|    |..|.|:       |||||..|.:...||.|.|:::|| |||
plant   431 ---------VSSDSNLRCQQLHSLHGK-------TVVSISAGKYWASAVTSTGEVYMWDGKN--- 476

  Fly   415 HLGLGHKKDQFFPFKAAING--KVTKVAYGVDHTIAL 449
                  .|| ..|..:.::.  :.|.||.|..|.:.:
plant   477 ------GKD-IAPSLSRLHNLKRATTVAVGETHLLVV 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	13/52 (25%)
		RCC1_2	159..188	CDD:290274	10/28 (36%)
		RCC1	175..233	CDD:278826	10/57 (18%)
		RCC1_2	220..249	CDD:290274	6/28 (21%)
		RCC1	236..286	CDD:278826	14/50 (28%)
		RCC1	290..341	CDD:278826	9/65 (14%)
		RCC1	345..395	CDD:278826	13/53 (25%)
		RCC1_2	386..414	CDD:290274	14/28 (50%)
		RCC1	402..449	CDD:278826	14/49 (29%)
AT3G03790	NP_001189802.1	ANK	29..137	CDD:238125
		Ank_2	29..126	CDD:289560
		ANK repeat	29..59	CDD:293786
		ANK repeat	61..92	CDD:293786
		ANK repeat	95..126	CDD:293786
		RCC1	154..201	CDD:278826
		RCC1	205..259	CDD:278826	20/124 (16%)
		RCC1	264..311	CDD:278826	10/56 (18%)
		RCC1	315..365	CDD:278826	14/49 (29%)
		SPOP_C_like	586..>615	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910