Protein Alignment CG3862 and RCC1L

DIOPT Version :10

• Sequence 1: NP_608550.1
• Gene: CG3862 / 33261
• FlyBaseID: FBgn0031286
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_110425.2
• Gene: RCC1L / 81554
• HGNCID: 14948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 182/457 - (39%)
• Similarity: 269/457 - (58%)
• Gaps: 26/457 - (5%)

  Fly    10 GISRSYTAKAKRGVLAQDKSKIKEYSPKTTDSHEH-----RVYVWGFQETGALGLQTNV------ 63
            |:.|.:...|.|....::.::.:...|......|.     ||:||||..:||||:.:.|
Human    20 GLGRGHWTAAGRSRSRREAAEAEAEVPVVQYVGERAARADRVFVWGFSFSGALGVPSFVVPSSGP 84

  Fly    64 -KKAKERYTEMVHH-PTRLQFSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGFQVK 126
             .:|..|....:.. |.||:.  :.:|:..|.|||||:.:....|...::|.|||.||||||. :
Human    85 GPRAGARPRRRIQPVPYRLEL--DQKISSAACGYGFTLLSSKTADVTKVWGMGLNKDSQLGFH-R 146

  Fly   127 GNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGR 191
            ...:.....:.::.|:.:.||.   :..::.||..:|.||||.:|||....:|::||||||||||
Human   147 SRKDKTRGYEYVLEPSPVSLPL---DRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGR 208

  Fly   192 SIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYH 256
            .::|.|.||:|..:||:...|     .:||||.||||||:|||.||.:|:||||||||||.|:|:
Human   209 KVVENEIYSESHRVHRMQDFD-----GQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYN 268

  Fly   257 TAGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQINIPRALKL 321
            .....|.:|||:....:::::...||.||::..|..||||||||.|| .|....||:|:||.|..
Human   269 ITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQL-ASVTDSTQVNVPRCLHF 332

  Fly   322 TKSIGKIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTV 386
            : .:||::..|.||:.|..||.:|.|:.||:||||.||.:.:::.|:.:.|.|||..:|:.|..|
Human   333 S-GVGKVRQAACGGTGCAVLNGEGHVFVWGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQV 396

  Fly   387 VSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKAAINGKVTKVAYGVDHTIALCK 451
            ..|.||:.|..|:.:.|:||:||||..|.||:|..:||:||::..:.|:...||.||||.:.|.|
Human   397 SRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHMVTLAK 461

  Fly   452 PF 453
            .|
Human   462 SF 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:395335	23/68 (34%)
		ATS1	89..449	CDD:444065	156/359 (43%)
RCC1L	NP_110425.2	ATS1	<55..274	CDD:444065	94/229 (41%)
		RCC1 1. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	58..124		23/67 (34%)
		RCC1 2. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	128..191		22/66 (33%)
		ATS1	178..>455	CDD:444065	132/283 (47%)
		RCC1 3. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	193..247		31/58 (53%)
		RCC1 4. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	248..300		23/51 (45%)
		RCC1 5. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	302..353		25/52 (48%)
		RCC1 6. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	354..411		23/56 (41%)
		RCC1 7. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	412..461		23/48 (48%)