DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3862 and rcbtb2

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_005173422.1	Gene:	rcbtb2 / 794652	ZFINID:	ZDB-GENE-071016-3	Length:	527	Species:	Danio rerio

Alignment Length:	330	Identity:	87/330 - (26%)
Similarity:	142/330 - (43%)	Gaps:	53/330 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMS 163
            :|....|:   :|..|.|....||.....:..:|..:|::.                ..::.|:|
Zfish    35 IYVTVNDE---VFALGTNCSGCLGLGDTQSTIEPRRIDILC----------------GKKIISLS 80

  Fly   164 AGRA-HLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQ 227
            .|.. |:|:.|.:|.::..|:|.|.|.|...      :...|...:...::.||  .|.:|.||.
Zfish    81 YGTGPHVVIATADGEVYAWGHNGYSQLGNGT------TNHGLTPALVSTNLIGK--RVTEVSCGS 137

  Fly   228 DHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQIT--LIGGDVEKEKIVRLSCSSDCVLALNEAG 290
            .|::.||..|.:|..|:...||.|.|:  ||.|.|  .:...::.:.:|.::|...|.:|:.:.|
Zfish   138 HHTIALTTDGEVYAWGYNNSGQVGSGS--TANQPTPRRVSSCLQNKVVVNIACGQLCSMAVLDNG 200

  Fly   291 DAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWG---F 352
            :.:|||.:..|||........|  .|..:...:.|..|: ||.|.:..:||.|:|.||:||   :
Zfish   201 ETYGWGYNCNGQLGLGNNGNQQ--TPCRIAALQGINIIQ-VACGYAHTLALTDEGFVYSWGANSY 262

  Fly   353 GILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNS-DGDLFMWGKNR---- 412
            |.||.|      :|....:|.|.   :...|..|....|...|..|..: .|.:.|||:.|
Zfish   263 GQLGTG------NKSNQAVPTLI---NMDKERMVEVAACHTSHTSAAKTQSGQVLMWGQCRGQAV 318

  Fly   413 -FGHL 416
             :.||
Zfish   319 AYPHL 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	87/330 (26%)
		RCC1_2	159..188	CDD:290274	10/29 (34%)
		RCC1	175..233	CDD:278826	14/57 (25%)
		RCC1_2	220..249	CDD:290274	10/28 (36%)
		RCC1	236..286	CDD:278826	14/51 (27%)
		RCC1	290..341	CDD:278826	14/50 (28%)
		RCC1	345..395	CDD:278826	15/52 (29%)
		RCC1_2	386..414	CDD:290274	9/33 (27%)
		RCC1	402..449	CDD:278826	7/20 (35%)
rcbtb2	XP_005173422.1	RCC1	40..89	CDD:278826	12/67 (18%)
		RCC1	93..143	CDD:278826	14/57 (25%)
		RCC1	146..196	CDD:278826	14/51 (27%)
		RCC1	199..248	CDD:278826	14/51 (27%)
		RCC1	251..299	CDD:278826	16/56 (29%)
		BTB	364..460	CDD:279045
		BTB	371..463	CDD:197585
		SPOP_C_like	463..521	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820