DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and hectd3

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001072497.1	Gene:	hectd3 / 779952	XenbaseID:	XB-GENE-5937967	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	166	Identity:	27/166 - (16%)
Similarity:	56/166 - (33%)	Gaps:	63/166 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 HRISQEDICGKEDEVVQ------------VECGQD--HSMFLTKKGRIYTCGWGADGQTGQGNYH 256
            |.:.|::..|...:.|:            :.|..|  |..:           |.:||..|:   |
Frog   213 HVVKQDESLGSVKQYVESISVSSATVENNLSCLTDGYHDTY-----------WESDGSHGE---H 263

  Fly   257 TAGQITLIGGDVEKEKIVRLSCSS---------------DCVLALNEAGDAFGWGNSEYGQLDDS 306
            .. |:.:..|.:.|..::.:..:.               |.:..:||.            .||::
Frog   264 WI-QLHMKEGTIVKRLLITVDSTDESYMPKGIVVYGGERDALKKINEV------------SLDEN 315

  Fly   307 ELAETQI------NIP-RALKLTKSIGKIKDVAAGG 335
            .:.:..|      ::| ..:|:|:.:.:..||...|
Frog   316 LIGDVCILEDMTTHLPIIEIKITQCLDEGIDVRIRG 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274
		RCC1	175..233	CDD:278826	7/40 (18%)
		RCC1_2	220..249	CDD:290274	6/42 (14%)
		RCC1	236..286	CDD:278826	9/64 (14%)
		RCC1	290..341	CDD:278826	9/53 (17%)
		RCC1	345..395	CDD:278826
		RCC1_2	386..414	CDD:290274
		RCC1	402..449	CDD:278826
hectd3	NP_001072497.1	APC10-HECTD3	222..355	CDD:176487	25/157 (16%)
hectd3	NP_001072497.1	HECTc	512..837	CDD:421431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010