DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and sergef

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001072233.1	Gene:	sergef / 779680	XenbaseID:	XB-GENE-6455308	Length:	349	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	86/332 - (25%)
Similarity:	136/332 - (40%)	Gaps:	70/332 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 ETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVL 172
            :.|:..|.|:..|||.   |:..|.....::|           |..:.:..::|:|||..|...:
Frog     9 QLLYAWGANSYGQLGV---GSTQDTPVPQLVI-----------GLPNHETVIRSISAGGGHSAAV 59

  Fly   173 TQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDIC------GKEDEVVQVECGQDHSM 231
            |::|.::..|.||.||.|             |.|.......|      |.  .|.:|.||.|.::
Frog    60 TESGRVYVCGQNSEGQLG-------------LDHTTDVTQFCLCPGALGL--RVSKVSCGWDFTL 109

  Fly   232 FLTKKGRIYTCGWGADGQTGQGNYHTAGQITL---IGGDVEKEKIVRLSCSSDCVLALNEAGDAF 293
            .|.:.|.:.:||.....|.|:..   ||:..:   :|  ::|.|::.::.....||||.:.|..|
Frog   110 ILAETGELLSCGANTYSQLGRAG---AGRSCVPRPVG--IQKRKVIDVAAGLRHVLALTDNGQIF 169

  Fly   294 GWGNSEYGQLDDSELAETQINIPRALKLTKS---------IGKIKDVAAGGSFCMALNDQGLVYT 349
            .||:   |....:.....|..||.....|:.         .||:  |.||...|:||:|.|.:|.
Frog   170 QWGS---GLASHARRFSPQNPIPPVYGATEPCPVPGMEGICGKV--VTAGSYHCVALSDAGDMYA 229

  Fly   350 WGFG----ILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGK 410
            ||..    :|...||         ||.|...:..|....::|::..|..|:.|....|.:|.||:
Frog   230 WGSNKHGQLLHPDPF---------LLHPHRVQAHFFLGESIVAVTSGWTHLVAQTDTGKVFTWGR 285

  Fly   411 NRFGHLG 417
            ..:..||
Frog   286 ANYSQLG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	10/28 (36%)
		RCC1	175..233	CDD:278826	16/63 (25%)
		RCC1_2	220..249	CDD:290274	9/28 (32%)
		RCC1	236..286	CDD:278826	12/52 (23%)
		RCC1	290..341	CDD:278826	15/59 (25%)
		RCC1	345..395	CDD:278826	13/53 (25%)
		RCC1_2	386..414	CDD:290274	8/27 (30%)
		RCC1	402..449	CDD:278826	6/16 (38%)
sergef	NP_001072233.1	RCC1	11..>294	CDD:332518	86/330 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010