DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and niki

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_651293.1	Gene:	niki / 42959	FlyBaseID:	FBgn0045980	Length:	841	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	82/343 - (23%)
Similarity:	130/343 - (37%)	Gaps:	97/343 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KRGVLAQDKSKIKEYS-------PKT-------TDSH------EHRVYVWGFQETGALGLQTNVK 64
            ||.||.|.|:....:|       ||.       :|||      :...|.||....|.|||
  Fly   427 KRSVLYQLKAFGTCFSMAPIQLPPKAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGL----- 486

  Fly    65 KAKERYTEMVHHPTRLQFSNNNEITDVAAGYGFTVYAVNRDDGETLFGSGLNTDSQLGFQVKGNP 129
            .|.|.:.   |:|:|::...|..:....||.|||:...   ...:|...|.|....||...:.|.
  Fly   487 TALEAWK---HYPSRMESVRNYHVVSACAGDGFTILVT---QAGSLLSCGSNAHLALGQDEQRNY 545

  Fly   130 NDP---ANLDVIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNSYGQCGR 191
            :.|   |.|                   .|:||:.::||..|::.|::.|.::..|.::.|..|.
  Fly   546 HSPKLIARL-------------------ADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGL 591

  Fly   192 SIIEEE--------------RYSK-------SALIHRISQEDICGKED----------------- 218
            ...:::              :.||       ||::....:..:||..|
  Fly   592 GNYQQQQKFPQKILLSHVKTKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLGFQRSAKITAFKK 656

  Fly   219 -----EVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRLSC 278
                 :|.|......||:||.:.|.:||.|..|:||.|..:.::....||: ..|:...||:.:|
  Fly   657 VQLPHKVTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNSVDHPTLV-DSVKSRYIVKANC 720

  Fly   279 SSDCVLALNEAGDAFGWG 296
            |..|.:..:|......||
  Fly   721 SDQCTIVASEDNIITVWG 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	17/55 (31%)
		RCC1_2	159..188	CDD:290274	7/28 (25%)
		RCC1	175..233	CDD:278826	15/100 (15%)
		RCC1_2	220..249	CDD:290274	11/28 (39%)
		RCC1	236..286	CDD:278826	16/49 (33%)
		RCC1	290..341	CDD:278826	2/7 (29%)
		RCC1	345..395	CDD:278826
		RCC1_2	386..414	CDD:290274
		RCC1	402..449	CDD:278826
niki	NP_651293.1	STKc_Nek	104..359	CDD:270855
		S_TKc	105..354	CDD:214567
		ATS1	445..747	CDD:227511	75/325 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010