DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Sergef

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_038956885.1	Gene:	Sergef / 365243	RGDID:	1563497	Length:	481	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	78/291 - (26%)
Similarity:	120/291 - (41%)	Gaps:	48/291 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 IFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTC 242
            :|..|.|||||.|..      :.:..|:.: ...|.| |...:..|..|..||:.:|..|.::.|
  Rat    17 LFAWGANSYGQLGLG------HKEDVLLPQ-QLSDFC-KSGCIKSVTGGGGHSVVVTDGGGLFVC 73

  Fly   243 GWGADGQTGQGNYHTAGQIT----LIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQL 303
            |...|||.|.|:.....:.|    |:|..:.     :::|..|..:.|.|.|.....|::.:|||
  Rat    74 GLNKDGQLGLGHTEEVLRFTICKPLLGCPIR-----QVACGWDFTIMLTEKGQVLSCGSNAFGQL 133

  Fly   304 DDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGFGILGFGPFVEQTSKPQ 368
            .... ...:..:|:|::..:.  |:..||||....:|..|.|..:.||.|:...|         :
  Rat   134 GVPH-GPRKCVVPQAIECLRE--KVVCVAAGLRHALATTDTGSTFQWGTGLASSG---------R 186

  Fly   369 HLLP----PLF------GRNDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKD 423
            .|.|    |||      .|......:|||....|..|..::...|:|::||:|:.|.|.   ...
  Rat   187 RLCPGQNLPLFLTAKEPSRVTGLESSTVVCAVAGSDHSASLTDTGELYVWGRNKHGQLA---SLA 248

  Fly   424 QFFPFKAAING------KVTKVAYGVDHTIA 448
            .|.|....:..      |||.|..|..|.:|
  Rat   249 TFLPLPQRVEAHYFQDEKVTAVWSGWTHLVA 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	5/9 (56%)
		RCC1	175..233	CDD:278826	16/54 (30%)
		RCC1_2	220..249	CDD:290274	9/28 (32%)
		RCC1	236..286	CDD:278826	13/53 (25%)
		RCC1	290..341	CDD:278826	12/50 (24%)
		RCC1	345..395	CDD:278826	15/59 (25%)
		RCC1_2	386..414	CDD:290274	9/27 (33%)
		RCC1	402..449	CDD:278826	16/53 (30%)
Sergef	XP_038956885.1	ATS1	17..>325	CDD:227511	78/291 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910