DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Herc3

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_001102101.1	Gene:	Herc3 / 362377	RGDID:	1307803	Length:	1050	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	90/334 - (26%)
Similarity:	154/334 - (46%)	Gaps:	35/334 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 GFQVKGNPNDPANLD-VIIYPTAIKLPRVQGETDEDMRVKSMSAGRAHLVVLTQNGTIFTLGNNS 185
            |:...|.|...:||. ::..|...:..       .|..:|.::.|..|.|.|.::|.::|.|.|:
  Rat     5 GYWSLGQPGISSNLQGIVAEPQVCRFV-------SDRSIKEVACGGNHSVFLLEDGEVYTCGVNT 62

  Fly   186 YGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQT 250
            .||.|    .|...:|...|..::       :..::.|.||:.||:.|:.:|::::.|.|:|||.
  Rat    63 KGQLG----HEREGNKPEQIGALA-------DQHIIHVACGESHSLALSDRGQLFSWGAGSDGQL 116

  Fly   251 GQGNYHTAGQITLIGGDVEKEKIVRLSCSSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQINI 315
            |......:..:..:...:.::.|:::||.:...|||...|..|.||.:.:|||...:...:|.:
  Rat   117 GLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTS- 180

  Fly   316 PRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGF---GILGFGPFVEQTSKPQHLLPPLFGR 377
            |:.::..:.| .:..|||||:...||:..|.|:.||.   |.||.....::.| |.|:
  Rat   181 PQRVRSLEGI-PLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRES-PCHV------- 236

  Fly   378 NDFSNETTVVSIGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKA--AINGKVTKVA 440
             .......||.|.||..|...:...|.:|.:|....|.||.....|:..|.:.  .:..:||::|
  Rat   237 -KLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIA 300

  Fly   441 YGVDHTIAL 449
            .|..||:||
  Rat   301 CGRQHTLAL 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	9/28 (32%)
		RCC1	175..233	CDD:278826	15/57 (26%)
		RCC1_2	220..249	CDD:290274	10/28 (36%)
		RCC1	236..286	CDD:278826	11/49 (22%)
		RCC1	290..341	CDD:278826	15/50 (30%)
		RCC1	345..395	CDD:278826	15/52 (29%)
		RCC1_2	386..414	CDD:290274	9/27 (33%)
		RCC1	402..449	CDD:278826	14/48 (29%)
Herc3	NP_001102101.1	ATS1	2..331	CDD:227511	90/334 (27%)
		RCC1	313..377	CDD:395335
		HECTc	702..1048	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920