DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and rcbtb1

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_956285.1	Gene:	rcbtb1 / 336007	ZFINID:	ZDB-GENE-030131-7951	Length:	531	Species:	Danio rerio

Alignment Length:	329	Identity:	84/329 - (25%)
Similarity:	144/329 - (43%)	Gaps:	48/329 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VYAVNRDDGETLFGSGLNTDSQLGFQVKGNPNDPANLDVIIYPTAIKLPRVQGETDEDMRVKSMS 163
            :|..:.|:   ::..|||..:.||.....:...|..||.:                ...::.|:|
Zfish    35 IYITHDDE---VYVLGLNCSNCLGTGDSQSTIAPKKLDCL----------------SGKKLISLS 80

  Fly   164 AGRA-HLVVLTQNGTIFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQ 227
            .|.. |::::|::|.::..|:|.|.|.|...      :...:...:...::.||  .|.:|.||.
Zfish    81 YGSGPHVLLVTEDGELYAWGHNGYSQLGNGT------TNQGVSPILVSTNLQGK--RVTEVSCGS 137

  Fly   228 DHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQIT--LIGGDVEKEKIVRLSCSSDCVLALNEAG 290
            .||:.||.:|.::..|:...||.|.|:  ||.|.|  .:...::.:.||.::|.....:|:.:.|
Zfish   138 HHSLALTHEGEVFAWGYNNCGQVGSGS--TANQPTPRKVSNCLQNKVIVNIACGQTSSMAVTDNG 200

  Fly   291 DAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWG---F 352
            :.:|||.:..|||...... .|:...|.:.|....  :..:|:|.:..:||.|:||:|.||   :
Zfish   201 EVYGWGYNGNGQLGLGNNG-NQLTPCRLIALQGFC--VLQIASGYAHSLALTDEGLLYAWGANTY 262

  Fly   353 GILGFGPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAVNS-DGDLFMWGKNRFGHL 416
            |.||.|....|.|..|.:.         ..|..|....|...|..|..: .|.::|||:.|...:
Zfish   263 GQLGTGNKSNQLSPVQVMT---------EKERIVEIAACHSTHTSAAKTQSGQVYMWGQCRGQAI 318

  Fly   417 GLGH 420
            .|.|
Zfish   319 VLPH 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826	84/329 (26%)
		RCC1_2	159..188	CDD:290274	9/29 (31%)
		RCC1	175..233	CDD:278826	14/57 (25%)
		RCC1_2	220..249	CDD:290274	10/28 (36%)
		RCC1	236..286	CDD:278826	13/51 (25%)
		RCC1	290..341	CDD:278826	12/50 (24%)
		RCC1	345..395	CDD:278826	15/52 (29%)
		RCC1_2	386..414	CDD:290274	9/28 (32%)
		RCC1	402..449	CDD:278826	7/19 (37%)
rcbtb1	NP_956285.1	RCC1	40..90	CDD:278826	13/68 (19%)
		RCC1_2	77..106	CDD:290274	9/28 (32%)
		RCC1	93..143	CDD:278826	14/57 (25%)
		RCC1	146..196	CDD:278826	13/51 (25%)
		RCC1	199..248	CDD:278826	12/51 (24%)
		RCC1	251..299	CDD:278826	16/56 (29%)
		BTB	360..464	CDD:279045
		BTB	371..467	CDD:197585
		SPOP_C_like	467..525	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820