DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Nek2

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	NP_572415.1	Gene:	Nek2 / 31696	FlyBaseID:	FBgn0029970	Length:	735	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	31/184 - (16%)
Similarity:	55/184 - (29%)	Gaps:	77/184 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 GDAFGWGNSEYGQLDDS--ELAETQINIPRAL--------------KLTKSIGKIKDVAAGG--- 335
            |:.|.|....|.:||::  :...::|::.|.|              :..||:..:.:..|||
  Fly    42 GELFAWKGMNYDELDEAKCDALVSEISVLRQLQHPNIVQYYHHLVNREAKSVYIVMECCAGGDLA 106

  Fly   336 -----------------------SFCMA------------------------LNDQGLVYTWGFG 353
                                   ..|.|                        |:..|......||
  Fly   107 QIVQRARSQRQRFEEPYIWRVLFQLCRALQVCHNKIPNGTILHRDIKPANIFLDAAGNAKLGDFG 171

  Fly   354 ILGF--------GPFVEQTSKPQHLLPPLFGRNDFSNETTVVSIGCGVFHMGAV 399
            :...        ..||   ..|.::.|.|.....:..::.|.::||.|:.|.|:
  Fly   172 LARMLRRDQSFAASFV---GTPHYMSPELVKGRKYDRKSDVWAVGCLVYEMCAL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274
		RCC1	175..233	CDD:278826
		RCC1_2	220..249	CDD:290274
		RCC1	236..286	CDD:278826
		RCC1	290..341	CDD:278826	16/116 (14%)
		RCC1	345..395	CDD:278826	12/57 (21%)
		RCC1_2	386..414	CDD:290274	6/14 (43%)
		RCC1	402..449	CDD:278826
Nek2	NP_572415.1	STKc_Nek2	18..281	CDD:270857	31/184 (17%)
Nek2	NP_572415.1	S_TKc	19..281	CDD:214567	31/184 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010