DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Ibtk

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_038938472.1	Gene:	Ibtk / 315858	RGDID:	1311697	Length:	1352	Species:	Rattus norvegicus

Alignment Length:	274	Identity:	65/274 - (23%)
Similarity:	112/274 - (40%)	Gaps:	44/274 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 QGETDEDMRVKSMSAGRAHLVVLTQNGT-IFTLGNNSYGQCGRSIIEEERYSKSALIHRISQEDI 213
            :|.:..|:.:|...   ||:|....:.| ::|.|:|:....|......:.:.:  |:...|:..:
  Rat   118 EGLSPLDLLMKDRP---AHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPE--LLDLFSRSRV 177

  Fly   214 CGKEDEVVQVECGQDHSMFLTKKGRIYTCGWGADGQTGQGNYHTAGQITLIGGDVEKEKIVRLSC 278
                 .|.||...:.||:||:::|::||||.|..|:.|.|:..|.....|:.| :......:::.
  Rat   178 -----YVKQVVLCKFHSVFLSQQGQVYTCGHGRGGRLGHGDEQTCLVPRLVEG-LSGHSCSQVAA 236

  Fly   279 SSDCVLALNEAGDAFGWGNSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALND 343
            :.|..:.|.|.|..:.:|.:.:.||.... ..:..|:||.::.....|:.....|.|.|...|..
  Rat   237 AKDHTVVLTEDGCVYTFGLNTFHQLGIIP-PPSSCNVPRQIQAKYLKGRTIIGVAAGRFHTVLWT 300

  Fly   344 QGLVYTWGF--GILGFGPFVEQTSKPQHLLPP-------------LFGRNDFSNETTVVSIGCGV 393
            :..|||.|.  |.||            |||.|             .....|.:......|.|..|
  Rat   301 REAVYTLGLNGGQLG------------HLLDPNGEKCVTTPRQVSALHHKDIAVSLVAASDGATV 353

  Fly   394 FHMGAVNSDGDLFM 407
                .|.:.||:::
  Rat   354 ----CVTTRGDIYL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	8/29 (28%)
		RCC1	175..233	CDD:278826	12/58 (21%)
		RCC1_2	220..249	CDD:290274	13/28 (46%)
		RCC1	236..286	CDD:278826	13/49 (27%)
		RCC1	290..341	CDD:278826	11/50 (22%)
		RCC1	345..395	CDD:278826	15/64 (23%)
		RCC1_2	386..414	CDD:290274	6/22 (27%)
		RCC1	402..449	CDD:278826	2/6 (33%)
Ibtk	XP_038938472.1	Ank_2	<45..116	CDD:403870
		ANK repeat	51..82	CDD:293786
		ANK repeat	84..116	CDD:293786
		ATS1	139..>341	CDD:227511	53/222 (24%)
		RCC1	247..299	CDD:395335	11/52 (21%)
		BTB1_POZ_IBtk	547..652	CDD:349610
		BTB2_POZ_IBtk	764..876	CDD:349611
		BACK_IBtk	872..931	CDD:350575
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000