DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3862 and Rccd1

DIOPT Version :9

Sequence 1:	NP_608550.1	Gene:	CG3862 / 33261	FlyBaseID:	FBgn0031286	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_006229517.1	Gene:	Rccd1 / 308760	RGDID:	1309901	Length:	378	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	75/394 - (19%)
Similarity:	129/394 - (32%)	Gaps:	146/394 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 QNGTIFTLGNNSYGQC-----GRSIIEEERYSKSALIHRISQEDICGKEDEVVQVECGQDHSMFL 233
            :.|..|..|...:||.     |:              |.:...:.....|:|.||.....::..:
  Rat     5 RQGAWFGFGFCGFGQALGSGNGQ--------------HAVHSPEPLHAADDVCQVSASWSYTALV 55

  Fly   234 TKKGRIYTCG------------WGADG-------QTGQGNYHTAGQITLIGGDVEKE-------- 271
            |:.||:...|            |.::|       ::|.|   |..|..:.|..::.|
  Rat    56 TRGGRVELSGSVSCAADGCRDVWASEGLLVVQRNKSGSG---TELQAWVPGSALQGEPLWVQNLA 117

  Fly   272 --------------------------------------------KIVRLSCSSDCVLALNEAGDA 292
                                                        ::.:|...::..|.|.|||..
  Rat   118 SGAKAQGEDEPGSEPRMGTLPLLPCARAYMTPQPPFCQPLAPELRVRQLQLGAEHALLLCEAGQV 182

  Fly   293 FGWGNSEYGQLDDSELAETQINIPRALKLTKSIGKIKDVAAGGSFCMALNDQGLVYTWGF----- 352
            |.||...:|||....| |.::. ||.|:..:.: ::.:|||||...:.:::.|.:|.||:
  Rat   183 FSWGGGRHGQLGHGSL-EAELE-PRLLEALQGL-RMAEVAAGGWHSVCVSETGDIYIWGWNESGQ 244

  Fly   353 ------------------------GILGFGPFVEQTSKPQHLL-----PPLFGRNDFSNETTVVS 388
                                    |:.|....:.....|.|.:     |.|.   |....:..|.
  Rat   245 LALPTRSGTEKKTVREEATELNDDGLRGEEAALADVGAPAHFIAIQPFPALL---DLPLGSDAVK 306

  Fly   389 IGCGVFHMGAVNSDGDLFMWGKNRFGHLGLGHKKDQFFPFKAAINGKVTKVAYGVDHTIAL---- 449
            ..||..|...|...|:|:.||..::|.  ||||       .:..:.:..:|.|.|:..:.:
  Rat   307 ASCGSRHTAVVTRTGELYTWGWGKYGQ--LGHK-------DSTSSDQPCRVEYFVERQLEVRAVT 362

  Fly   450 CKPF 453
            |.|:
  Rat   363 CGPW 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3862	NP_608550.1	RCC1	43..99	CDD:278826
		RCC1_2	159..188	CDD:290274	3/13 (23%)
		RCC1	175..233	CDD:278826	11/62 (18%)
		RCC1_2	220..249	CDD:290274	9/47 (19%)
		RCC1	236..286	CDD:278826	13/120 (11%)
		RCC1	290..341	CDD:278826	17/50 (34%)
		RCC1	345..395	CDD:278826	14/83 (17%)
		RCC1_2	386..414	CDD:290274	9/27 (33%)
		RCC1	402..449	CDD:278826	12/46 (26%)
Rccd1	XP_006229517.1	RCC1_2	163..192	CDD:290274	9/28 (32%)
		RCC1	180..228	CDD:278826	17/50 (34%)
		RCC1_2	218..244	CDD:290274	9/25 (36%)
		RCC1_2	305..333	CDD:290274	9/27 (33%)
		RCC1	321..368	CDD:278826	14/55 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910